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Gene Page - CG Number : CG10805
Gene Summary - CG10805:

CG10805: The gene lethal (2) k09022 is referred to in FlyBase by the symbol Dmel\l(2)k09022 (CG10805, FBgn0086451). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: neurogenesis. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Armadillo-like helical; Armadillo-type fold; BP28, C-terminal domain; U3 small nucleolar RNA-associated protein 10. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.

Gene summary for CG10805 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10805:CG10805 is perturbed in following parameters in primary screen: Fclc NuCirc NuSize Tclc Tmph2
CG10805 is perturbed in following parameters in classification assay (fluid): CellSize-(fld) LP_Fint1+ LP_Fint2+ NuCellD+(fld) NuSize-(fld) Okt+(fld) SP_Fclc-
CG10805 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Fint1+ Fint2+ Fint3+ Rto1-(tfr) Tint3+ Tint4-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10805.
Cell Count:
CG_NumberCategoryR1R2R3
CG10805Primary screen480962841
CG10805Secondary assay11461339976
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10805:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201783.496796208-0.31642764-0.9955015450.149147995-0.53394963-0.851177079-1.499728978-1.234769389-0.9263253752.4724774421.106315665-0.230389993-0.0185501951.8273599015.104736447-0.8357546980.8679882223.2687348961.742423602-0.6615941560.120079121-0.573059867-0.295802969
202238-0.053922671-0.002415238-0.319363764-0.2029945031.5270336772.4087824961.7566819152.5912504933.3562288670.3307281472.69999328-0.2635497251.6560883371.8874017451.0029532931.5763236021.4437127562.4341263021.3015576863.7486504172.473144817.2143126493.950899983
203880.134811849-0.0187295850.1179838710.530839941-0.1416058664.8278624744.053003683.7255488794.5438294410.3910289325.053945437-0.5451731120.9653140120.9319077722.0788279640.4319192192.5266128047.7117076354.093100145.859628270.2609366226.9791352115.266399146
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10805Slide10C0.1051.0451.1561.235
CG10805Slide10O0.0461.0571.0911.103
CG10805Slide10P0.2020.9901.2721.315
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse


Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10805Slide1F0.0451.1451.1441.310
CG10805Slide1O0.1901.1261.0091.172
CG10805Slide1T0.1371.1491.4131.097
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG10805 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
neurogenesisGO:0022008inferred from mutant phenotype
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cellular_componentGO:0005575no biological data available
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
bindingGO:0005488inferred from electronic annotation with InterPro:IPR011989, InterPro:IPR016024
Other annotations
DatabaseLink
FlyBaseClick here to see CG10805 in FlyBase
FLIGHTClick here to see CG10805 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10805 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10805
Entrez GeneEntrez Gene page for CG10805
UniprotUniprot page for CG10805

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)