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Gene Page - CG Number : CG10806
Gene Summary - CG10806:

CG10806: The gene Na+/H+ hydrogen antiporter 1 is referred to in FlyBase by the symbol Dmel\Nha1 (CG10806, FBgn0031865). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: sodium:hydrogen antiporter activity. There is experimental evidence that it is involved in the biological process: renal sodium ion transport. 6 alleles are reported. The phenotype of these alleles is annotated with: adult Malpighian tubule. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Cation/H+ exchanger. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during late larval stages.

Gene summary for CG10806 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10806:CG10806 is perturbed in following parameters in primary screen: NuCirc NuSize
CG10806 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10806.
Cell Count:
CG_NumberCategoryR1R2R3
CG10806Primary screen649929895
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10806:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201792.138088298-0.880286967-0.792546172-0.6515949910.466304378-2.112756287-0.941270912-1.085858260.3307377510.133456910.6511861450.2097066431.928179059-0.5019451112.4458487771.0340614660.8386579642.3922715581.649047609-0.160875019-0.6853024111.8717069971.145407864
2022370.4470948172.3896291464.0058863130.7141896472.5804493584.6333559993.7010671814.318684743.552307146-0.4228149950.5596080770.0387863130.1627631352.174999894-0.1671713111.8263451490.1581855970.208480952-0.4264154563.7189903880.3280806765.6320347623.605815821
203870.0265911850.393777776-0.1960981280.0933826632.331273139-0.618732151.060603984-0.86564695-0.0848359840.485203963-0.18119443-0.064629194-0.1604084080.051687720.6661543041.7598466010.570874853-0.273776799-0.5288990470.3149723961.276613634.9962923235.387792411
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10806 is not tested in classification assay
Integrated Annotations for CG10806 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
renal sodium ion transportGO:0003096inferred from mutant phenotype
transmembrane transport
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
brush borderGO:0005903inferred from direct assay
integral to membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sodium:hydrogen antiporter activityGO:0015385inferred from sequence or structural similarity with EMBL:AE000854
sodium:hydrogen antiporter activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10806 in FlyBase
FLIGHTClick here to see CG10806 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10806 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10806
Entrez GeneEntrez Gene page for CG10806
UniprotUniprot page for CG10806

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)