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Gene Page - CG Number : CG1081
Gene Summary - CG1081:

CG1081: The gene Rheb is referred to in FlyBase by the symbol Dmel\Rheb (CG1081, FBgn0041191). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: GTPase activity. There is experimental evidence for 13 unique biological process terms, many of which group under: biological regulation; cellular component organization or biogenesis; growth; cellular process; developmental growth; positive regulation of ribosome biogenesis; energy taxis; response to nutrient levels; cell cycle; response to light stimulus; response to starvation; cell cycle process; positive regulation of cellular biosynthetic process; neuron differentiation. 34 alleles are reported. The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: organ system; organ system subdivision; multicellular structure; cell cycle; adult segment; external compound sense organ; cellular process; adult; cell cycle process; peripheral nervous system. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Ras type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in stages of adults of both sexes.

Gene summary for CG1081 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1081:CG1081 is not perturbed in primary screen.
CG1081 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1081.
Cell Count:
CG_NumberCategoryR1R2R3
CG1081Primary screen443618168
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1081:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG1081 is not tested in classification assay
Integrated Annotations for CG1081 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
imaginal disc growthGO:0007446inferred from mutant phenotype
response to starvation
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
membraneGO:0016020inferred from electronic annotation with InterPro:IPR020849
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
GTPase activityGO:0003924inferred from sequence or structural similarity
GTPase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG1081 in FlyBase
FLIGHTClick here to see CG1081 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1081 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1081
Entrez GeneEntrez Gene page for CG1081
UniprotUniprot page for CG1081

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)