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Gene Page - CG Number : CG10840
Gene Summary - CG10840:

CG10840: The gene eIF5B is referred to in FlyBase by the symbol Dmel\eIF5B (CG10840, FBgn0026259). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. Based on sequence similarity, it is predicted to be involved in the biological process: translational initiation. 13 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Elongation factor, GTP-binding domain; Small GTP-binding protein domain; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation/initiation factor/Ribosomal, beta-barrel; Translation initiation factor IF- 2; Translation initiation factor IF- 2, domain 3. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in stages of adults of both sexes.

Gene summary for CG10840 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10840:CG10840 is not perturbed in primary screen.
CG10840 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10840.
Cell Count:
CG_NumberCategoryR1R2R3
CG10840Primary screen667490481
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10840:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201920.007977306-0.522006935-0.665722137-0.7666031060.0052479371.4387141691.2518457121.1567254051.307594723-0.316797958-0.058994184-0.016623701-0.6001139820.168825757-0.5262870920.788999772-0.6786566980.051737392-0.423594561.1437575660.8860547861.0830482040.537061041
2021341.375296610.6849841550.30759874-0.452033417-0.218279246-0.6910797910.531866559-0.563315389-1.2221205410.235489332-1.297711847-0.2568192050.5522717990.0950564861.912720566-0.1698273460.488832066-1.1110003382.086538094-0.54508205-0.5993021985.8308479581.04125198
203440.1232142080.004875834-0.44457396-0.36686927-0.1691405490.9840163370.5039073060.9909767470.8649633990.0215623140.462014874-0.0029976550.21281547-0.1684241670.206988099-0.2853261992.0200268490.249538275-0.2349772190.7895218371.5748562051.337660477-0.42953031
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10840 is not tested in classification assay
Integrated Annotations for CG10840 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
translational initiationGO:0006413inferred from sequence or structural similarity
translational initiation
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoplasmGO:0005737inferred from sequence or structural similarity
cytosol
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
translation initiation factor activityGO:0003743inferred from sequence or structural similarity
DEAD/H-box RNA helicase binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10840 in FlyBase
FLIGHTClick here to see CG10840 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10840 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10840
Entrez GeneEntrez Gene page for CG10840
UniprotUniprot page for CG10840

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)