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Gene Page - CG Number : CG10849
Gene Summary - CG10849:

CG10849: The gene Sc2 is referred to in FlyBase by the symbol Dmel\Sc2 (CG10849, FBgn0035471). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: oxidoreductase activity, acting on the CH-CH group of donors. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: lipid metabolic process. 16 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal; Ubiquitin supergroup. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 12-18 embryonic stages, during early larval stages, in adult male stages.

Gene summary for CG10849 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10849:CG10849 is perturbed in following parameters in primary screen: NuFluct
CG10849 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10849.
Cell Count:
CG_NumberCategoryR1R2R3
CG10849Primary screen4005591044
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10849:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201980.526597684-0.700932729-0.347266305-0.413311857-0.870964704-3.357870007-2.831667803-2.046446143-2.8196289940.35275111.040908953-0.368884782-0.041609473-0.108562440.220276102-0.541407053-0.194465582.125647739-0.630011577-2.94413803-0.888523947-0.1179276361.2814756
2022480.4133590650.3605413610.193635495-0.2993348591.178194259-1.9773056330.130661966-2.325001288-2.2807574920.057768139-0.268577735-0.192101374-0.69279463-0.1268887061.6143818261.574194306-1.072661564-0.255732895-0.947404205-3.0036895491.8363523812.991677531.758598557
203380.801849576-0.1071454250.252144329-0.4322190771.9899004472.1757115121.3160561822.6344552333.631455741.0154754471.3941296971.6097098931.478056562.5267944762.0317625532.174229191.0850587413.2634577960.4337379243.2264385871.3079955110.046173167.753337293
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10849 is not tested in classification assay
Integrated Annotations for CG10849 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
lipid metabolic processGO:0006629inferred from electronic annotation with InterPro:IPR001104
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021inferred from electronic annotation with InterPro:IPR001104
cytoplasm
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
oxidoreductase activity, acting on the CH-CH group of donorsGO:0016627inferred from electronic annotation with InterPro:IPR001104
Other annotations
DatabaseLink
FlyBaseClick here to see CG10849 in FlyBase
FLIGHTClick here to see CG10849 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10849 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10849
Entrez GeneEntrez Gene page for CG10849
UniprotUniprot page for CG10849

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)