.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10850Gene Summary - CG10850:CG10850: The gene imaginal discs arrested is referred to in FlyBase by the symbol Dmel\ida (CG10850, FBgn0041147). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: mitotic anaphase-promoting complex activity. There is experimental evidence that it is involved in the biological process: imaginal disc development; positive regulation of mitotic metaphase/anaphase transition; neurogenesis. 13 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; imaginal precursor; multicellular structure; cell cycle; cellular component organization or biogenesis; cell cycle process; eo support cell; salivary gland imaginal ring; organ system subdivision; sense organ; tracheal system; larval head segment; adult segment. It has one annotated transcript and one annotated polypeptide. Protein features are: Anaphase-promoting complex subunit 5,TPR-containing domain; Tetratricopeptide-like helical. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages. Gene summary for CG10850 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10850:CG10850 is perturbed in following parameters in primary screen: Fclc Fmph3 Tclc Tint4 CG10850 is perturbed in following parameters in classification assay (fluid): Rto1- SP_Fint1- CG10850 is perturbed in following parameters in classification assay (transferrin): Fmph1- Fmph3- Okt+(tfr) Rto1-(tfr) Rto2-(tfr) Rto3-(tfr) Tint4- Tmph1- Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10850.Cell Count:CG_NumberCategoryR1R2R3CG10850Primary screen796940958CG10850Secondary assay8969051063R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10850: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize201991.549515457-0.135250695-0.1555421950.3507863240.7661250541.8239533631.5011555691.682412961.7343129541.202209993.092833810.1814053460.0493721570.3111477131.0881561981.2967747261.3640597222.8560395980.6720275892.1477793680.6564388362.9439130141.8698518752022470.876123216-0.162636422-0.0275404010.3170418621.1876451912.5044649212.3182442963.0237497093.2505181240.7656808563.579177850.6719830711.5057795470.6784845593.9715210862.3850672530.9934277561.6139446311.0027080013.2015075084.5332805752.5633385822.69113950320337-0.0200003860.5667140760.168516141.300086791.251884583.1001236181.9391236613.1475984224.8144204412.3402762284.030893236-0.2012542351.7396464062.6536409920.4320760341.3414971543.3329182188.654465913.9165655254.7416619432.9759680337.6723919125.071925149 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):Fluid:CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3CG10850Slide20C0.9830.9721.0670.955CG10850Slide20O0.6570.9981.0131.149CG10850Slide20P0.3400.9870.9800.817C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex PulseTransferrin:CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3CG10850Slide1F0.4671.2681.1661.083CG10850Slide1O0.0521.7801.5611.466CG10850Slide1T0.1550.4650.5240.227F=Fdex; O=Surface TfR (Okt9); T=TfIntegrated Annotations for CG10850 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidencemitotic anaphaseGO:0000090non-traceable author statement imaginal disc developmentGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidenceanaphase-promoting complexGO:0005680non-traceable author statement anaphase-promoting complexGene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidencebindingGO:0005488inferred from electronic annotation with InterPro:IPR011990 Other annotations DatabaseLinkFlyBaseClick here to see CG10850 in FlyBaseFLIGHTClick here to see CG10850 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10850 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10850Entrez GeneEntrez Gene page for CG10850UniprotUniprot page for CG10850 Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)
.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10850Gene Summary - CG10850:CG10850: The gene imaginal discs arrested is referred to in FlyBase by the symbol Dmel\ida (CG10850, FBgn0041147). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: mitotic anaphase-promoting complex activity. There is experimental evidence that it is involved in the biological process: imaginal disc development; positive regulation of mitotic metaphase/anaphase transition; neurogenesis. 13 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; imaginal precursor; multicellular structure; cell cycle; cellular component organization or biogenesis; cell cycle process; eo support cell; salivary gland imaginal ring; organ system subdivision; sense organ; tracheal system; larval head segment; adult segment. It has one annotated transcript and one annotated polypeptide. Protein features are: Anaphase-promoting complex subunit 5,TPR-containing domain; Tetratricopeptide-like helical. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages. Gene summary for CG10850 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10850:CG10850 is perturbed in following parameters in primary screen: Fclc Fmph3 Tclc Tint4 CG10850 is perturbed in following parameters in classification assay (fluid): Rto1- SP_Fint1- CG10850 is perturbed in following parameters in classification assay (transferrin): Fmph1- Fmph3- Okt+(tfr) Rto1-(tfr) Rto2-(tfr) Rto3-(tfr) Tint4- Tmph1- Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10850.Cell Count:CG_NumberCategoryR1R2R3CG10850Primary screen796940958CG10850Secondary assay8969051063R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10850: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize201991.549515457-0.135250695-0.1555421950.3507863240.7661250541.8239533631.5011555691.682412961.7343129541.202209993.092833810.1814053460.0493721570.3111477131.0881561981.2967747261.3640597222.8560395980.6720275892.1477793680.6564388362.9439130141.8698518752022470.876123216-0.162636422-0.0275404010.3170418621.1876451912.5044649212.3182442963.0237497093.2505181240.7656808563.579177850.6719830711.5057795470.6784845593.9715210862.3850672530.9934277561.6139446311.0027080013.2015075084.5332805752.5633385822.69113950320337-0.0200003860.5667140760.168516141.300086791.251884583.1001236181.9391236613.1475984224.8144204412.3402762284.030893236-0.2012542351.7396464062.6536409920.4320760341.3414971543.3329182188.654465913.9165655254.7416619432.9759680337.6723919125.071925149 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):Fluid:CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3CG10850Slide20C0.9830.9721.0670.955CG10850Slide20O0.6570.9981.0131.149CG10850Slide20P0.3400.9870.9800.817C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex PulseTransferrin:CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3CG10850Slide1F0.4671.2681.1661.083CG10850Slide1O0.0521.7801.5611.466CG10850Slide1T0.1550.4650.5240.227F=Fdex; O=Surface TfR (Okt9); T=TfIntegrated Annotations for CG10850 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidencemitotic anaphaseGO:0000090non-traceable author statement imaginal disc developmentGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidenceanaphase-promoting complexGO:0005680non-traceable author statement anaphase-promoting complexGene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidencebindingGO:0005488inferred from electronic annotation with InterPro:IPR011990 Other annotations DatabaseLinkFlyBaseClick here to see CG10850 in FlyBaseFLIGHTClick here to see CG10850 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10850 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10850Entrez GeneEntrez Gene page for CG10850UniprotUniprot page for CG10850
CG10850: The gene imaginal discs arrested is referred to in FlyBase by the symbol Dmel\ida (CG10850, FBgn0041147). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: mitotic anaphase-promoting complex activity. There is experimental evidence that it is involved in the biological process: imaginal disc development; positive regulation of mitotic metaphase/anaphase transition; neurogenesis. 13 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; imaginal precursor; multicellular structure; cell cycle; cellular component organization or biogenesis; cell cycle process; eo support cell; salivary gland imaginal ring; organ system subdivision; sense organ; tracheal system; larval head segment; adult segment. It has one annotated transcript and one annotated polypeptide. Protein features are: Anaphase-promoting complex subunit 5,TPR-containing domain; Tetratricopeptide-like helical. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages.
Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)