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Gene Page - CG Number : CG10851
Gene Summary - CG10851:

CG10851: The gene B52 is referred to in FlyBase by the symbol Dmel\B52 (CG10851, FBgn0004587). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: mRNA splicing, via spliceosome; regulation of mRNA splicing, via spliceosome; mitosis; regulation of alternative mRNA splicing, via spliceosome. 23 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; organ system subdivision; adult; adult segment; multicellular structure; sense organ; external compound sense organ; thoracic segment; anatomical structure; region of integument. It has 10 annotated transcripts and 10 annotated polypeptides. Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG10851 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10851:CG10851 is not perturbed in primary screen.
CG10851 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10851.
Cell Count:
CG_NumberCategoryR1R2R3
CG10851Primary screen409679728
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10851:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201100-0.5603862420.8424290111.296124350.372776913-0.281271557-1.32314393-1.349324824-0.8849198621.14668992.9060442282.944599652-0.0437892430.5100625270.4314227170.690053113-1.2767103311.7247583116.0378267942.6594564751.576808208-0.177300361-0.231199728-0.30015224
20224635.8494735726.6444317824.24869532-0.3622151290.9905622291.8126179310.8833750041.7796818562.126061248-0.3717496960.322384186-0.3407074590.3580175790.7634099090.9880646551.071336805-0.883486418-0.803997343-0.1342587161.8855359081.8777074264.5788390380.56492061
203360.3521196190.4811343040.466360382-0.2040873521.2197897561.7330980720.9183741481.9024615552.48054957-0.3840546531.9755818050.472603595-0.4569550530.0656521230.0074799971.6136719270.920019751.934335522-0.610692732.7817832012.2077816942.2012231241.930135044
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10851 is not tested in classification assay
Integrated Annotations for CG10851 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
nuclear mRNA splicing, via spliceosomeGO:0000398inferred from direct assay
mRNA splice site selection
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
omega speckleGO:0035062NOT inferred from direct assay
nuclear speck
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
mRNA bindingGO:0003729non-traceable author statement
protein binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10851 in FlyBase
FLIGHTClick here to see CG10851 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10851 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10851
Entrez GeneEntrez Gene page for CG10851
UniprotUniprot page for CG10851

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)