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Gene Page - CG Number : CG10890
Gene Summary - CG10890:

CG10890: The gene mutagen-sensitive 201 is referred to in FlyBase by the symbol Dmel\mus201 (CG10890, FBgn0002887). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: single-stranded DNA specific endodeoxyribonuclease activity. Based on sequence similarity, it is predicted to be involved in the biological process: base-excision repair. 12 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: 5'-3' exonuclease, C-terminal domain; DNA repair protein (XPGC)/yeast Rad; Helix-hairpin-helix motif, class 2; Ubiquitin interacting motif; XPG N-terminal; XPG conserved site; XPG/RAD2 endonuclease; Xeroderma pigmentosum group G protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.

Gene summary for CG10890 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10890:CG10890 is not perturbed in primary screen.
CG10890 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10890.
Cell Count:
CG_NumberCategoryR1R2R3
CG10890Primary screen659200608
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10890:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201117-0.179544526-0.633980501-0.396205475-0.3450561760.5441055631.0237718281.5694344941.1138319361.655031928-0.1587397551.47231351335.1559179331.3852993934.691117279.9233844470.383419159-0.2358167430.5026713310.1975031191.7632841151.5998431712.1532836581.065240756
2022590.2521635120.512129717-0.886699790.72876176-0.56451839-0.880856277-1.14076256-1.146237058-0.897736035-0.2157427630.916992877-0.508379425-1.067755156-0.7695534740.52681377-0.629221906-0.5192128951.540323689-0.422070591-1.068573551.0819941754.3121362793.714573303
20349-0.3651227741.110776530.570907461-0.5138980740.1689381352.3032488381.9609023522.2825089382.074542081-0.904852163-0.216335168-0.635141639-0.412781633-0.1616636560.058067821.0506282-0.24180267-0.2002911070.1231419392.756983276-0.36869961-0.066108998-0.239661094
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10890 is not tested in classification assay
Integrated Annotations for CG10890 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
base-excision repairGO:0006284inferred from sequence or structural similarity with SGD_LOCUS:RAD2; SGD:S0003490
nucleotide-excision repair
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from electronic annotation with InterPro:IPR001044
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
single-stranded DNA specific endodeoxyribonuclease activityGO:0000014inferred from sequence or structural similarity with SGD_LOCUS:RAD2; SGD:S0003490
single-stranded DNA binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10890 in FlyBase
FLIGHTClick here to see CG10890 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10890 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10890
Entrez GeneEntrez Gene page for CG10890
UniprotUniprot page for CG10890

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)