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Gene Page - CG Number : CG10899
Gene Summary - CG10899:

CG10899: This gene is referred to in FlyBase by the symbol Dmel\CG10899 (FBgn0039235). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: carbonate dehydratase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: one-carbon metabolic process. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Alpha carbonic anhydrase; Carbonic anhydrase, alpha-class; Carbonic anhydrase, alpha-class, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected. Peak expression observed during late pupal stages, in adult male stages.

Gene summary for CG10899 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10899:CG10899 is perturbed in following parameters in primary screen: NuSize
CG10899 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10899.
Cell Count:
CG_NumberCategoryR1R2R3
CG10899Primary screen327571483
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10899:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2011202.1564682890.243995273-0.6599337340.366419029-1.387061872-4.723295688-2.641242937-3.7760585920.49149676321.37572176-0.74345484120.2340762919.1921057419.601951370.461629049-1.4406154270.271101478-0.2427443121.261117763-1.129107223-0.0810318674.5580138585.441508295
2022562.9351953370.564078741-0.0622469032.1249883050.0764294881.0154438361.4947977691.234672980.6794133220.164329234-0.12346716-0.085917321-0.075888125-0.3751441011.944285610.7054247720.818295301-0.5027237531.3164468860.2628460941.5128832115.4251434930.977941745
203460.4358702150.311084414-0.0208746250.4441066270.3069139820.820662624-0.0769269340.8875965690.881407425-0.685294695-0.398929231-0.001859395-0.435959482-0.0064167390.4725399460.3400887570.3076280170.642520844-0.4700725130.513009061.7380214216.4681659422.470734571
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10899 is not tested in classification assay
Integrated Annotations for CG10899 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
one-carbon metabolic processGO:0006730inferred from electronic annotation with InterPro:IPR018338
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
carbonate dehydratase activityGO:0004089inferred from sequence or structural similarity with UniProtKB:P08060 AND inferred from sequence or structural similarity with UniProt:Q8UWA5
zinc ion binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10899 in FlyBase
FLIGHTClick here to see CG10899 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10899 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10899
Entrez GeneEntrez Gene page for CG10899
UniprotUniprot page for CG10899

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)