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Gene Page - CG Number : CG1090
Gene Summary - CG1090:

CG1090: This gene is referred to in FlyBase by the symbol Dmel\CG1090 (FBgn0037238). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: calcium, potassium:sodium antiporter activity. Based on sequence similarity, it is predicted to be involved in the biological process: calcium ion transport; sodium ion transport. 13 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Sodium/calcium exchanger membrane region; Sodium/potassium/calcium exchanger. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late pupal stages.

Gene summary for CG1090 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1090:CG1090 is not perturbed in primary screen.
CG1090 is perturbed in following parameters in classification assay (fluid): LP_Fclc+ LP_Fint1+ SP_Fclc+ SP_Fint1+ SP_Fint2+ SP_Fmph1+ SP_Fmph2+ SP_Fmph3+
CG1090 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1090.
Cell Count:
CG_NumberCategoryR1R2R3
CG1090Primary screen666924887
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1090:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG1090Slide8C0.7951.0100.9900.937
CG1090Slide8O0.2241.1811.0461.023
CG1090Slide8P0.8921.0331.0680.934
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG1090 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
sodium ion transportGO:0006814inferred from sequence or structural similarity with UniProtKB:Q9U6A0
calcium ion transport
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021inferred from sequence or structural similarity with UniProtKB:Q9U6A0
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
calcium, potassium:sodium antiporter activityGO:0008273inferred from sequence or structural similarity with UniProtKB:Q28139
calcium, potassium:sodium antiporter activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG1090 in FlyBase
FLIGHTClick here to see CG1090 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1090 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1090
Entrez GeneEntrez Gene page for CG1090
UniprotUniprot page for CG1090

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)