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Gene Page - CG Number : CG10910
Gene Summary - CG10910:

CG10910: This gene is referred to in FlyBase by the symbol Dmel\CG10910 (FBgn0034289). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: regulation of DNA-dependent transcription, elongation; regulation of transcription from RNA polymerase II promoter. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Transcription elongation factor Spt6. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed at stages throughout the larval period.

Gene summary for CG10910 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10910:CG10910 is perturbed in following parameters in primary screen: Fclc Fint1 Fint2 Fint3 Fint4 Fmph1 Fmph2 Fmph3 Fnum Rto1 Rto2 Rto3 Tclc Tint1 Tint2 Tint3 Tint4 Tmph1 Tmph2 Tmph3
CG10910 is perturbed in following parameters in classification assay (fluid): CellSize-(fld) LP_Fclc- LP_Fint1- LP_Fint2- LP_Fint3- LP_Fint4- LP_Fmph1- LP_Fmph2- LP_Fnum- NuCellD+(fld) NuCirc+(fld) NuSize-(fld) SP_Fclc- SP_Fint1- SP_Fint2- SP_Fint3- SP_Fmph1- SP_Fmph2- SP_Fmph3- SP_Fnum-
CG10910 is perturbed in following parameters in classification assay (transferrin): Fclc- Fint1- Fint2- Fint3- Fint4- Fmph1- Fmph2- Fmph3- Fnum- NuCellD+(tfr) Okt+(tfr) Rto1-(tfr) Rto2-(tfr) Rto3-(tfr) Tclc- Tint1- Tint2- Tint3-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10910.
Cell Count:
CG_NumberCategoryR1R2R3
CG10910Primary screen584584703
CG10910Secondary assay9839291094
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10910:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
20112510.2886622214.587498616.930679413.9053338765.93744044826.8484739321.3195482932.0744577921.957634229.685563644.2037710233.3518285312.7029221674.149340509-0.4843805611.2435539910.2417507216.7454114513.0637709518.186794911.6522539220.7574303562.411567968
2022814.38409791911.5523311613.216059465.7954537565.74187882814.4741289214.1283669522.0930870812.868578617.424602454.1870369415.1520913656.9121469784.4167384390.2779935911.3462578884.93243534111.453061524.3352695769.920428270.5682223793.9807747942.790913241
203113.96908945610.2910957711.026114451.0378735055.13432477118.0469993313.8411731625.5146237113.425675184.9401805643.0459761695.4677380386.1997488366.6016603340.2665134331.6321284117.81812961115.2015163910.0650289713.360268550.4646033111.8627764812.530365122
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10910Slide10C0.0030.6290.7720.640
CG10910Slide10O0.7940.9441.0500.974
CG10910Slide10P0.0000.5800.5870.535
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse


Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10910Slide2F0.0000.3470.3580.318
CG10910Slide2O0.0061.1641.2301.298
CG10910Slide2T0.0010.4270.2360.418
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG10910 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
regulation of transcription from RNA polymerase II promoterGO:0006357inferred from electronic annotation with InterPro:IPR017072
regulation of transcription elongation, DNA-dependent
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
-
Other annotations
DatabaseLink
FlyBaseClick here to see CG10910 in FlyBase
FLIGHTClick here to see CG10910 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10910 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10910
Entrez GeneEntrez Gene page for CG10910
UniprotUniprot page for CG10910

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)