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Gene Page - CG Number : CG10922
Gene Summary - CG10922:

CG10922: The gene La autoantigen-like is referred to in FlyBase by the symbol Dmel\La (CG10922, FBgn0011638). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: 5S rRNA primary transcript binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: RNA processing. 4 alleles are reported. The phenotypes of these alleles are annotated with: midgut constriction 2; trichogen cell; midgut constriction; midgut constriction 1; midgut constriction 3. It has one annotated transcript and one annotated polypeptide. Protein features are: Lupus La protein; Nucleotide-binding, alpha-beta plait; RNA recognition motif domain; RNA-binding motif; RNA-binding protein Lupus La; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 06-12 hour embryonic stages, during early larval stages, in adult female stages.

Gene summary for CG10922 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10922:CG10922 is perturbed in following parameters in primary screen: NuCirc NuSize
CG10922 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10922.
Cell Count:
CG_NumberCategoryR1R2R3
CG10922Primary screen790664765
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10922:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201133-0.242292902-0.528479151-0.7017007340.221330429-0.167478348-1.353578471-0.019682945-1.413520341-0.994223310.324026037-0.5574863210.995699130.2910941241.1146156691.4054941220.945894074-0.248542698-0.3168714230.055590589-0.6439848840.819081516-0.047211818-0.235412517
202273-0.26125195-0.53618878-0.573137733-0.505508580.9547039831.8280888261.3390123242.2679390742.5018560610.3444398812.2563030920.1066604861.3366605831.2975793651.0557394651.5528678180.6545164862.6051298850.8440610612.4710908290.22393948810.157645215.230877996
2033-0.503269902-0.5879085490.2996225570.0075248321.2987170821.7596387420.4940606491.9221317741.389424921-0.623902087-0.224059324-0.5064015191.0728545761.7263363310.3522315050.8674054110.467893663-0.411767562-0.1786910381.5369647740.005911588.1168548664.110545775
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10922 is not tested in classification assay
Integrated Annotations for CG10922 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
RNA processingGO:0006396inferred from electronic annotation with InterPro:IPR002344
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634non-traceable author statement
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
5S rRNA primary transcript bindingGO:0008098inferred from direct assay
5S rRNA primary transcript binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10922 in FlyBase
FLIGHTClick here to see CG10922 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10922 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10922
Entrez GeneEntrez Gene page for CG10922
UniprotUniprot page for CG10922

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)