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Gene Page - CG Number : CG10954
Gene Summary - CG10954:

CG10954: The gene Actin-related protein 2/3 complex, subunit 2 is referred to in FlyBase by the symbol Dmel\Arpc2 (CG10954, FBgn0032859). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of cytoskeleton; actin binding. There is experimental evidence that it is involved in the biological process: regulation of cell shape; lateral inhibition; cell projection assembly; cortical actin cytoskeleton organization; cell morphogenesis. 7 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Arp2/3 complex, 34kDa subunit p34-Arc. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.

Gene summary for CG10954 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10954:CG10954 is not perturbed in primary screen.
CG10954 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10954.
Cell Count:
CG10954Primary screen749394633
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10954:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10954 is not tested in classification assay
Integrated Annotations for CG10954 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
lateral inhibitionGO:0046331inferred from mutant phenotype
regulation of cell shape
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
Arp2/3 protein complexGO:0005885inferred from sequence or structural similarity with SGD_LOCUS:ARC35; SGD:S0005318
Arp2/3 protein complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
actin bindingGO:0003779inferred from sequence or structural similarity
actin binding
Other annotations
FlyBaseClick here to see CG10954 in FlyBase
FLIGHTClick here to see CG10954 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10954 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10954
Entrez GeneEntrez Gene page for CG10954
UniprotUniprot page for CG10954

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)