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Gene Page - CG Number : CG10955
Gene Summary - CG10955:

CG10955: The gene Rtf1 is referred to in FlyBase by the symbol Dmel\Rtf1 (CG10955, FBgn0034722). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding. There is experimental evidence that it is involved in the biological process: positive regulation of Notch signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of histone H3-K4 methylation. 8 alleles are reported. The phenotypes of these alleles are annotated with: mesothoracic tergum; wing. It has one annotated transcript and one annotated polypeptide. Protein features are: Plus-3; Plus-3 domain, subgroup. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG10955 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10955:CG10955 is perturbed in following parameters in primary screen: NuCirc NuSize
CG10955 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10955.
Cell Count:
CG_NumberCategoryR1R2R3
CG10955Primary screen551600613
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10955:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2011541.243345124-0.416272787-0.935328317-0.492767264-0.592127561-0.468935871-1.438020646-0.1328903350.540650371-0.293734113-1.0976842663.1786279873.0357889793.187629278-0.4986917040.3262216821.391804133-0.3027761170.090541126-0.4695444322.7949080046.1956255177.122584316
202132-0.380337767-0.508420435-0.1781446670.0983814810.5944615940.072192055-0.047851070.222147982-1.0815973181.500874395-0.5167258710.484554123-0.851970777-0.3771586330.3930721480.861605335-1.2304357790.052189383-1.440620694-0.810086055-0.4365463892.112315587-0.160057141
2032820.9653432470.296806220.035505081-0.0097619410.863504880.1947488050.2250271360.3824152550.911035702-0.617480966-0.6536824940.176617611-0.300464375-0.4974604030.740127110.3167174760.5565274090.303984530.3119244951.123212950.5520235077.2008649134.679005559
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10955 is not tested in classification assay
Integrated Annotations for CG10955 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
positive regulation of histone H3-K4 methylationGO:0051571inferred from mutant phenotype
positive regulation of Notch signaling pathway
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from direct assay
transcriptionally active chromatin
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
DNA bindingGO:0003677inferred from electronic annotation with InterPro:IPR004343, InterPro:IPR018144
Other annotations
DatabaseLink
FlyBaseClick here to see CG10955 in FlyBase
FLIGHTClick here to see CG10955 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10955 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10955
Entrez GeneEntrez Gene page for CG10955
UniprotUniprot page for CG10955

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)