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Gene Page - CG Number : CG10956
Gene Summary - CG10956:

CG10956: The gene Serpin 53F is referred to in FlyBase by the symbol Dmel\Spn53F (CG10956, FBgn0034195). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: serine-type endopeptidase inhibitor activity. There is experimental evidence that it is involved in the biological process: multicellular organism reproduction. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Serpin domain; Serpin family. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed in adult male stages.

Gene summary for CG10956 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10956:CG10956 is perturbed in following parameters in primary screen: NuSize
CG10956 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10956.
Cell Count:
CG_NumberCategoryR1R2R3
CG10956Primary screen689755768
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10956:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201155-0.356932603-0.558990381-0.4215283530.8368695940.2394977331.4294065720.6550464271.3730099010.818901666-0.286540387-0.072776318-0.050726345-0.0126849890.1890525570.595408576-0.154998845-0.840505220.0167619130.3353424111.3154288140.0046947662.2957302541.216733032
2021310.5567368330.135238656-0.181321368-0.4694036891.106462060.9407713120.2010484121.0739298941.0721063841.6971883460.8681096340.129341550.4641554420.1095212211.8163645161.1294096880.7248624661.4608608240.7051963510.7397933280.5164984023.2368785692.140923335
2032810.193456697-0.047208727-0.1544522690.5999328791.24028131.990481441.1701183022.2161594762.118771629-0.341153424-0.078837341-0.2134529750.63029110.859921968-0.0874940091.0479232811.1628727870.1524409550.8389000472.6432807060.3462135748.1359313344.130993579
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10956 is not tested in classification assay
Integrated Annotations for CG10956 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
negative regulation of proteolysisGO:0045861inferred from sequence or structural similarity
multicellular organism reproduction
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
extracellular spaceGO:0005615inferred from sequence model
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
serine-type endopeptidase inhibitor activityGO:0004867inferred from sequence or structural similarity
serine-type endopeptidase inhibitor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10956 in FlyBase
FLIGHTClick here to see CG10956 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10956 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10956
Entrez GeneEntrez Gene page for CG10956
UniprotUniprot page for CG10956

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)