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Gene Page - CG Number : CG10986
Gene Summary - CG10986:

CG10986: The gene garnet is referred to in FlyBase by the symbol Dmel\g (CG10986, FBgn0001087). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: protein transporter activity. There is experimental evidence that it is involved in the biological process: Notch receptor processing; endocytosis; determination of adult lifespan; eye pigment granule organization; compound eye pigmentation; eye pigment biosynthetic process; ocellus pigment biosynthetic process; negative regulation of gene silencing by RNA; ommochrome biosynthetic process. 74 alleles are reported. The phenotypes of these alleles are annotated with: eye; testis sheath; Malpighian tubule; pigment granule; pigment cell. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Adaptor protein complex AP-3, delta subunit; Armadillo-like helical; Armadillo-type fold; Bovine leukaemia virus receptor; Clathrin/coatomer adaptor, adaptin-like, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.

Gene summary for CG10986 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10986:CG10986 is not perturbed in primary screen.
CG10986 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10986.
Cell Count:
CG_NumberCategoryR1R2R3
CG10986Primary screen613761545
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10986:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2011731.27563026-0.172486053-0.3457151170.2128061680.40509560.8942851570.3974244160.7234346890.496705199-0.0516601650.632780223-0.240053006-0.232973691-0.7053369720.8508939570.983700699-0.1660602460.0743928810.1860774520.8841894371.218104416-0.644695703-0.682960513
202143-0.1408710480.009410213-0.0867702370.2706591861.5626840871.7016146110.7783118191.8887677511.5666629950.2301971680.9870327360.0585103720.8397169410.721148-0.1728683070.7158557980.074818212-0.6839514272.4761265431.347931726-0.3540422512.0967474151.864079822
2032930.268187059-0.172098497-0.354425608-0.0439043140.8177589021.3442953690.1685917771.2115316252.6265932872.5306326271.4828944950.4440261042.3727073252.584000047-0.4654121210.1849691220.3159274153.4829253820.0375941382.2460074010.1278589125.7997896977.062626621
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10986 is not tested in classification assay
Integrated Annotations for CG10986 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
determination of adult lifespanGO:0008340inferred from mutant phenotype
eye pigment biosynthetic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
AP-3 adaptor complexGO:0030123non-traceable author statement
clathrin adaptor complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein transporter activityGO:0008565inferred from electronic annotation with InterPro:IPR017105
binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10986 in FlyBase
FLIGHTClick here to see CG10986 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10986 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10986
Entrez GeneEntrez Gene page for CG10986
UniprotUniprot page for CG10986

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)