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Gene Page - CG Number : CG10990
Gene Summary - CG10990:

CG10990: The gene Programmed cell death 4 ortholog is referred to in FlyBase by the symbol Dmel\Pdcd4 (CG10990, FBgn0030520). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: germarium-derived female germ-line cyst formation; positive regulation of stem cell differentiation. 23 alleles are reported. The phenotype of these alleles is annotated with: germarium. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Armadillo-type fold; Initiation factor eIF-4 gamma, MA3. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages.

Gene summary for CG10990 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10990:CG10990 is not perturbed in primary screen.
CG10990 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10990.
Cell Count:
CG10990Primary screen537648670
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10990:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10990 is not tested in classification assay
Integrated Annotations for CG10990 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
germarium-derived female germ-line cyst formationGO:0030727inferred from mutant phenotype
positive regulation of stem cell differentiation
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
bindingGO:0005488inferred from electronic annotation with InterPro:IPR016024
Other annotations
FlyBaseClick here to see CG10990 in FlyBase
FLIGHTClick here to see CG10990 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10990 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10990
Entrez GeneEntrez Gene page for CG10990
UniprotUniprot page for CG10990

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)