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Gene Page - CG Number : CG11049
Gene Summary - CG11049:

CG11049: The gene shaven is referred to in FlyBase by the symbol Dmel\sv (CG11049, FBgn0005561). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity. There is experimental evidence that it is involved in the biological process: positive regulation of transcription from RNA polymerase II promoter; regulation of R7 cell differentiation; dendrite morphogenesis; neuron development; regulation of retinal cone cell fate specification; muscle organ development. 54 alleles are reported. The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; adult segment; eo support cell; adult; organ system; rhabdomere R7; cell part; imaginal precursor. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Homeodomain-like; Paired domain; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages.

Gene summary for CG11049 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11049:CG11049 is not perturbed in primary screen.
CG11049 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11049.
Cell Count:
CG_NumberCategoryR1R2R3
CG11049Primary screen829540173
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11049:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2012040.360684841-0.112709016-0.643849997-0.4501027720.900909865-0.780075099-0.207699919-0.0689943480.2358106130.628136803-0.7556491660.316672253-0.123782550.0720887351.1274779621.238013948-0.458650396-0.166149992-0.1187899230.2070514140.0560398452.301234821.297319719
202112-0.159912128-0.119567258-0.473791512-0.2680484430.098158585-0.734119975-1.040232004-0.984663006-1.170444959-1.099156196-0.5742834370.8973957121.8559812871.890548174-0.2373967690.942774788-1.637229422-0.5219762-0.248356435-1.6797288920.2172422751.338095108-0.343169227
2032620.713955431-0.8375162430.1879857460.419119327-0.985548778-2.230039541-2.376135644-2.894020134-2.3407831492.1204812870.2723340752.2721595623.5697908264.573828397-0.611831443-0.394071203-0.379593136-1.0022339460.305422747-3.6654831461.1136554213.9475145448.678554746
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11049 is not tested in classification assay
Integrated Annotations for CG11049 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
regulation of transcription, DNA-dependentGO:0006355non-traceable author statement
compound eye cone cell fate commitment
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634non-traceable author statement
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA binding transcription factor activityGO:0003700traceable author statement
sequence-specific distal enhancer binding RNA polymerase II transcription factor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11049 in FlyBase
FLIGHTClick here to see CG11049 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11049 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11049
Entrez GeneEntrez Gene page for CG11049
UniprotUniprot page for CG11049

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)