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Gene Page - CG Number : CG11055
Gene Summary - CG11055:

CG11055: The gene Hormone-sensitive lipase ortholog is referred to in FlyBase by the symbol Dmel\Hsl (CG11055, FBgn0034491). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: triglyceride lipase activity. There is experimental evidence that it is involved in the biological process: triglyceride mobilization. 5 alleles are reported. The phenotype of these alleles is annotated with: lipid particle. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Alpha/beta hydrolase fold-3; Hormone-sensitive lipase, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG11055 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11055:CG11055 is not perturbed in primary screen.
CG11055 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11055.
Cell Count:
CG_NumberCategoryR1R2R3
CG11055Primary screen557123762
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11055:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201207-0.519880186-0.65242309-0.725763459-0.3673922290.314146683-0.85472034-1.091255292-0.410388024-0.2129407481.6986429420.0174338570.4204538330.430207777-0.4532105742.096019492-0.2992309511.715411530.0504879730.4705138220.113215253-0.4164912460.6204454530.927197854
202109-0.6222514250.370720126-0.887182677-0.313286046-1.790886625-2.392079215-2.843496189-2.724445726-4.114977797-2.314279645-2.468025630.524295515-1.378182013-1.407137248-0.047612744-0.995558817-1.377493183-1.766267735-2.374070971-4.445531967-1.0321112-0.309540708-0.135961708
2032590.6248851080.243712029-0.5351602460.5132400361.4124321381.608872370.86148431.936889952.25724944-0.459820902-0.598980429-0.576096335-0.709821082-0.5490037710.0875201751.2584279590.2411812150.151312921-0.0937118272.615971291.2302425675.6727881592.129327596
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11055 is not tested in classification assay
Integrated Annotations for CG11055 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
lipid catabolic processGO:0016042inferred from electronic annotation with InterPro:IPR010468
cholesterol metabolic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
lipid particleGO:0005811inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
triglyceride lipase activityGO:0004806inferred from sequence or structural similarity with UniProtKB:P15304
Other annotations
DatabaseLink
FlyBaseClick here to see CG11055 in FlyBase
FLIGHTClick here to see CG11055 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11055 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11055
Entrez GeneEntrez Gene page for CG11055
UniprotUniprot page for CG11055

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)