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Gene Page - CG Number : CG11063
Gene Summary - CG11063:

CG11063: The gene Ajuba LIM protein is referred to in FlyBase by the symbol Dmel\jub (CG11063, FBgn0030530). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ligand-dependent nuclear receptor binding; thyroid hormone receptor binding; actin binding. There is experimental evidence that it is involved in the biological process: positive regulation of imaginal disc growth; hippo signaling cascade; positive regulation of organ growth. 8 alleles are reported. The phenotypes of these alleles are annotated with: eye; wing blade; wing. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Zinc finger, LIM-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG11063 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11063:CG11063 is not perturbed in primary screen.
CG11063 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11063.
Cell Count:
CG_NumberCategoryR1R2R3
CG11063Primary screen782575644
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11063:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201213-0.349568381-0.731537003-0.2110067140.1347749170.749986721.4429523030.6569737411.2968105280.4570911231.7174038870.359061492-0.551645350.0620896170.3609304040.5129191351.170948907-0.266958966-0.3188318480.6265357541.4447174831.3124120980.0786833360.960894726
202731.833526951.3869600351.144678521-0.15918977-0.046895771.5453957681.1213640881.4751435721.2452442770.6678055832.723633889-0.2369380370.5697577690.6663582961.9184442250.2197951132.9398934671.9285032071.1664865161.167585863-0.3950048022.675004552-0.424911395
2032230.0073707651.1032570050.70709053-0.4073209090.7342020561.8282979450.9040070841.8364372551.974119234-0.022162279-0.151765202-0.073251833-0.192845662.0810180850.400594910.7308246420.6546287841.2658204620.646388861.863614162-0.4957118763.6494777251.019704329
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11063 is not tested in classification assay
Integrated Annotations for CG11063 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
positive regulation of organ growthGO:0046622inferred from mutant phenotype
positive regulation of imaginal disc growth
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
adherens junctionGO:0005912inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ligand-dependent nuclear receptor bindingGO:0016922inferred from sequence or structural similarity with EMBL:L40374
thyroid hormone receptor binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11063 in FlyBase
FLIGHTClick here to see CG11063 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11063 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11063
Entrez GeneEntrez Gene page for CG11063
UniprotUniprot page for CG11063

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)