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Gene Page - CG Number : CG11066
Gene Summary - CG11066:

CG11066: The gene scarface is referred to in FlyBase by the symbol Dmel\scaf (CG11066, FBgn0033033). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process: imaginal disc-derived male genitalia morphogenesis. 11 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; adult head. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Peptidase S1/S6, chymotrypsin/Hap; Peptidase S1A, chymotrypsin-type; Peptidase cysteine/serine, trypsin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages.

Gene summary for CG11066 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11066:CG11066 is perturbed in following parameters in primary screen: NuSize
CG11066 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11066.
Cell Count:
CG_NumberCategoryR1R2R3
CG11066Primary screen663573535
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11066:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2012150.7691206620.3642306780.267768837-0.5511910450.651562505-0.490594885-0.354373476-0.1969160811.4924402020.8620668171.3104964520.181753731.8301561392.8113431720.71701917-0.04078981-0.3768372950.470553739-0.2282135730.814175280.4675276734.7870652784.499339207
202712.1612958380.5741336750.1901428030.7279535720.409523533-1.632461821.002481722-2.233026844-2.4662276830.522572331-0.4147452350.022695680.473356755-0.096641640.5095613310.771981210.864073888-0.3597607112.94340338-0.867107361-0.472821665.9126641871.093702788
203221-0.365967995-0.0917520920.4431374110.3152774670.5271407530.6790672480.0758085550.7490945581.4888158280.221483244-0.16667703-0.723008642-0.4163290350.307586786-0.6305333860.4344500870.3974153550.3373509630.4063295620.7743348533.8408790534.4601751652.374290071
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11066 is not tested in classification assay
Integrated Annotations for CG11066 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
imaginal disc-derived male genitalia morphogenesisGO:0048803inferred from mutant phenotype
proteolysis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
extracellular spaceGO:0005615inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
serine-type endopeptidase activityGO:0004252NOT non-traceable author statement
serine-type endopeptidase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11066 in FlyBase
FLIGHTClick here to see CG11066 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11066 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11066
Entrez GeneEntrez Gene page for CG11066
UniprotUniprot page for CG11066

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)