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Gene Page - CG Number : CG11070
Gene Summary - CG11070:

CG11070: This gene is referred to in FlyBase by the symbol Dmel\CG11070 (FBgn0028467). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: ubiquitin-ubiquitin ligase activity. Based on sequence similarity, it is predicted to be involved in the biological process: ubiquitin-dependent protein catabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: U box domain; Ubiquitin conjugation factor E4, core; Zinc finger, RING/FYVE/PHD-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.

Gene summary for CG11070 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11070:CG11070 is not perturbed in primary screen.
CG11070 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11070.
Cell Count:
CG_NumberCategoryR1R2R3
CG11070Primary screen572420542
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11070:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201217-0.381596454-1.150548733-0.36766806-0.1270624840.1200618060.7738959790.6936833990.7528684970.223144090.5330010451.0780739250.6229474080.201624446-0.719794218-0.165714844-0.014674864-0.395607156-0.149632450.0976986770.531857961-0.479712408-0.650436441-0.799118004
20269-0.4660043130.419712537-0.098427326-0.510412238-0.4863838440.285758033-0.6419376030.269934124-1.269352893-0.471892397-0.7880744150.1513852840.104744802-0.5993197110.195609323-0.152628883-0.614199202-0.158268552-0.453716557-1.264717631-0.3426524821.290670818-0.406399188
203219-0.344397222-0.4513279710.203510840.3730875630.394349307-0.678038855-0.009383125-0.68127423-1.358526153-0.544832413-0.564796874-0.08423926-0.3421481520.235100623-0.5228768920.302702933-0.476296159-0.747612812-1.822084255-1.13942544.2472928130.7331734170.115854742
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11070 is not tested in classification assay
Integrated Annotations for CG11070 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
ubiquitin-dependent protein catabolic processGO:0006511inferred from sequence or structural similarity with SGD_LOCUS:UFD2; SGD:S0002349
protein ubiquitination
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
ubiquitin ligase complexGO:0000151inferred from electronic annotation with InterPro:IPR003613, InterPro:IPR019474
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ubiquitin-ubiquitin ligase activityGO:0034450inferred from electronic annotation with InterPro:IPR019474
Other annotations
DatabaseLink
FlyBaseClick here to see CG11070 in FlyBase
FLIGHTClick here to see CG11070 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11070 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11070
Entrez GeneEntrez Gene page for CG11070
UniprotUniprot page for CG11070

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)