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Gene Page - CG Number : CG1108
Gene Summary - CG1108:

CG1108: The gene α-Esterase-6 is referred to in FlyBase by the symbol Dmel\α-Est6 (CG1108, FBgn0015574). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: carboxylesterase activity. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Carboxylesterase, type B. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed in adult male stages.

Gene summary for CG1108 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1108:CG1108 is perturbed in following parameters in primary screen: Fclc
CG1108 is perturbed in following parameters in classification assay (fluid): LP_Fint1+ LP_Fint2+ LP_Fint3+ Rto1- SP_Fint4-
CG1108 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Fint1+ Fint4- Rto2-(tfr) Rto3-(tfr) Tclc- Tint2- Tint3- Tint4-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1108.
Cell Count:
CG_NumberCategoryR1R2R3
CG1108Primary screen462826387
CG1108Secondary assay716721782
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1108:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG1108Slide10C0.0161.4041.4731.215
CG1108Slide10O0.3981.0101.0061.358
CG1108Slide10P0.2921.4231.2820.928
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse


Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG1108Slide10F0.0961.1291.0651.036
CG1108Slide10O0.7380.8571.0501.022
CG1108Slide10T0.5360.9530.7741.040
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG1108 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
-
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
carboxylesterase activityGO:0004091non-traceable author statement
carboxylesterase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG1108 in FlyBase
FLIGHTClick here to see CG1108 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1108 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1108
Entrez GeneEntrez Gene page for CG1108
UniprotUniprot page for CG1108

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)