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Gene Page - CG Number : CG11081
Gene Summary - CG11081:

CG11081: The gene plexin A is referred to in FlyBase by the symbol Dmel\plexA (CG11081, FBgn0025741). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; 14-3-3 protein binding. There is experimental evidence that it is involved in the biological process: axon guidance; semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance; axon midline choice point recognition. 21 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system subdivision; organ system; peripheral nervous system; multicellular structure; adult segment; organelle; thoracic segment; non-connected developing system; actin cytoskeleton; larval abdominal segment; imaginal precursor. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Cell surface receptor IPT/TIG; Immunoglobulin E-set; Immunoglobulin-like fold; Plexin; Plexin, cytoplasmic RasGAP domain; Plexin-like fold; Plexin/semaphorin/integrin; Rho GTPase activation protein; Semaphorin/CD100 antigen; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-18 hour embryonic stages.

Gene summary for CG11081 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11081:CG11081 is not perturbed in primary screen.
CG11081 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11081.
Cell Count:
CG11081Primary screen579402759
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11081:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11081 is not tested in classification assay
Integrated Annotations for CG11081 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
axon midline choice point recognitionGO:0016199inferred from mutant phenotype
axon guidance
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
intracellularGO:0005622inferred from electronic annotation with InterPro:IPR008936
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
axon guidance receptor activityGO:0008046non-traceable author statement
semaphorin receptor activity
Other annotations
FlyBaseClick here to see CG11081 in FlyBase
FLIGHTClick here to see CG11081 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11081 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11081
Entrez GeneEntrez Gene page for CG11081
UniprotUniprot page for CG11081

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)