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Gene Page - CG Number : CG11084
Gene Summary - CG11084:

CG11084: The gene prickle is referred to in FlyBase by the symbol Dmel\pk (CG11084, FBgn0003090). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: establishment or maintenance of cell polarity; establishment of imaginal disc-derived wing hair orientation; establishment of ommatidial planar polarity; morphogenesis of a polarized epithelium. 102 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: adult segment; organ system subdivision; thoracic segment; organ system; appendage segment; external compound sense organ; metatarsus; integumentary specialisation; peripheral nervous system; acellular anatomical structure; sense organ. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: PET domain; Zinc finger, LIM-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period.

Gene summary for CG11084 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11084:CG11084 is not perturbed in primary screen.
CG11084 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11084.
Cell Count:
CG11084Primary screen500425541
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11084:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11084 is not tested in classification assay
Integrated Annotations for CG11084 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
establishment of ommatidial planar polarityGO:0042067inferred from mutant phenotype
establishment or maintenance of cell polarity
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoplasmGO:0005737traceable author statement
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
zinc ion bindingGO:0008270inferred from electronic annotation with InterPro:IPR001781, InterPro:IPR010442
Other annotations
FlyBaseClick here to see CG11084 in FlyBase
FLIGHTClick here to see CG11084 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11084 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11084
Entrez GeneEntrez Gene page for CG11084
UniprotUniprot page for CG11084

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)