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Gene Page - CG Number : CG11093
Gene Summary - CG11093:

CG11093: The gene fussel is referred to in FlyBase by the symbol Dmel\fuss (CG11093, FBgn0039932). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: co-SMAD binding. There is experimental evidence that it is involved in the biological process: negative regulation of BMP signaling pathway; imaginal disc-derived wing vein specification. 11 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; mushroom body; sensillum campaniformium of dorsal radius; posterior crossvein; wing; mushroom body gamma neuron; mushroom body vertical lobe; mushroom body alpha/beta neuron; wing vein; wing vein L2. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: DNA binding domain, putative; SAND domain-like; Transcription regulator SKI/SnoN; Transforming protein Ski; c-SKI SMAD4-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, in adult female stages.

Gene summary for CG11093 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11093:CG11093 is perturbed in following parameters in primary screen: NuCirc NuSize
CG11093 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11093.
Cell Count:
CG_NumberCategoryR1R2R3
CG11093Primary screen3331235899
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11093:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201227-0.6398132570.1880002640.376750189-1.240751991-1.299211252-4.348035209-3.262331492-3.323197479-0.192803396-0.105578327-0.432638123-0.26620409-0.829477690.191335241.632960164-0.691532075-0.4071524630.2740451791.900080904-4.30741369-0.1055650840.06400998-0.638151071
202892.20414236-0.0505619630.3991214840.186737352.6379835942.3480873341.522277682.6460824492.8713401070.6118844460.3527492880.1145401553.7603701912.6269223013.2600259872.2422821740.0989473740.2200422130.1487181892.4809359162.79688375710.917246027.024707961
203239-0.595534235-0.386041007-0.159434479-0.1347749911.188205872.7315695691.4113548062.8823677062.76113386-0.144047371-0.1681637141.211988828-0.2525139570.2163555690.3287796791.4458929341.1748189120.586649951.3673854842.9761751210.9525618755.6453241874.217984548
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11093 is not tested in classification assay
Integrated Annotations for CG11093 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
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Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from electronic annotation with InterPro:IPR003380, InterPro:IPR010919
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
SMAD bindingGO:0046332inferred from electronic annotation with InterPro:IPR014890
nucleotide binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11093 in FlyBase
FLIGHTClick here to see CG11093 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11093 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11093
Entrez GeneEntrez Gene page for CG11093
UniprotUniprot page for CG11093

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)