.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG11093Gene Summary - CG11093:CG11093: The gene fussel is referred to in FlyBase by the symbol Dmel\fuss (CG11093, FBgn0039932). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: co-SMAD binding. There is experimental evidence that it is involved in the biological process: negative regulation of BMP signaling pathway; imaginal disc-derived wing vein specification. 11 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; mushroom body; sensillum campaniformium of dorsal radius; posterior crossvein; wing; mushroom body gamma neuron; mushroom body vertical lobe; mushroom body alpha/beta neuron; wing vein; wing vein L2. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: DNA binding domain, putative; SAND domain-like; Transcription regulator SKI/SnoN; Transforming protein Ski; c-SKI SMAD4-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, in adult female stages. Gene summary for CG11093 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG11093:CG11093 is perturbed in following parameters in primary screen: NuCirc NuSize CG11093 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11093.Cell Count:CG_NumberCategoryR1R2R3CG11093Primary screen3331235899R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG11093: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize201227-0.6398132570.1880002640.376750189-1.240751991-1.299211252-4.348035209-3.262331492-3.323197479-0.192803396-0.105578327-0.432638123-0.26620409-0.829477690.191335241.632960164-0.691532075-0.4071524630.2740451791.900080904-4.30741369-0.1055650840.06400998-0.638151071202892.20414236-0.0505619630.3991214840.186737352.6379835942.3480873341.522277682.6460824492.8713401070.6118844460.3527492880.1145401553.7603701912.6269223013.2600259872.2422821740.0989473740.2200422130.1487181892.4809359162.79688375710.917246027.024707961203239-0.595534235-0.386041007-0.159434479-0.1347749911.188205872.7315695691.4113548062.8823677062.76113386-0.144047371-0.1681637141.211988828-0.2525139570.2163555690.3287796791.4458929341.1748189120.586649951.3673854842.9761751210.9525618755.6453241874.217984548 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG11093 is not tested in classification assayIntegrated Annotations for CG11093 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidence-Gene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidencenucleusGO:0005634inferred from electronic annotation with InterPro:IPR003380, InterPro:IPR010919Gene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidenceSMAD bindingGO:0046332inferred from electronic annotation with InterPro:IPR014890 nucleotide binding Other annotations DatabaseLinkFlyBaseClick here to see CG11093 in FlyBaseFLIGHTClick here to see CG11093 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG11093 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG11093Entrez GeneEntrez Gene page for CG11093UniprotUniprot page for CG11093 Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)
.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG11093Gene Summary - CG11093:CG11093: The gene fussel is referred to in FlyBase by the symbol Dmel\fuss (CG11093, FBgn0039932). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: co-SMAD binding. There is experimental evidence that it is involved in the biological process: negative regulation of BMP signaling pathway; imaginal disc-derived wing vein specification. 11 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; mushroom body; sensillum campaniformium of dorsal radius; posterior crossvein; wing; mushroom body gamma neuron; mushroom body vertical lobe; mushroom body alpha/beta neuron; wing vein; wing vein L2. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: DNA binding domain, putative; SAND domain-like; Transcription regulator SKI/SnoN; Transforming protein Ski; c-SKI SMAD4-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, in adult female stages. Gene summary for CG11093 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG11093:CG11093 is perturbed in following parameters in primary screen: NuCirc NuSize CG11093 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11093.Cell Count:CG_NumberCategoryR1R2R3CG11093Primary screen3331235899R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG11093: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize201227-0.6398132570.1880002640.376750189-1.240751991-1.299211252-4.348035209-3.262331492-3.323197479-0.192803396-0.105578327-0.432638123-0.26620409-0.829477690.191335241.632960164-0.691532075-0.4071524630.2740451791.900080904-4.30741369-0.1055650840.06400998-0.638151071202892.20414236-0.0505619630.3991214840.186737352.6379835942.3480873341.522277682.6460824492.8713401070.6118844460.3527492880.1145401553.7603701912.6269223013.2600259872.2422821740.0989473740.2200422130.1487181892.4809359162.79688375710.917246027.024707961203239-0.595534235-0.386041007-0.159434479-0.1347749911.188205872.7315695691.4113548062.8823677062.76113386-0.144047371-0.1681637141.211988828-0.2525139570.2163555690.3287796791.4458929341.1748189120.586649951.3673854842.9761751210.9525618755.6453241874.217984548 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG11093 is not tested in classification assayIntegrated Annotations for CG11093 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidence-Gene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidencenucleusGO:0005634inferred from electronic annotation with InterPro:IPR003380, InterPro:IPR010919Gene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidenceSMAD bindingGO:0046332inferred from electronic annotation with InterPro:IPR014890 nucleotide binding Other annotations DatabaseLinkFlyBaseClick here to see CG11093 in FlyBaseFLIGHTClick here to see CG11093 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG11093 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG11093Entrez GeneEntrez Gene page for CG11093UniprotUniprot page for CG11093
CG11093: The gene fussel is referred to in FlyBase by the symbol Dmel\fuss (CG11093, FBgn0039932). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: co-SMAD binding. There is experimental evidence that it is involved in the biological process: negative regulation of BMP signaling pathway; imaginal disc-derived wing vein specification. 11 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; mushroom body; sensillum campaniformium of dorsal radius; posterior crossvein; wing; mushroom body gamma neuron; mushroom body vertical lobe; mushroom body alpha/beta neuron; wing vein; wing vein L2. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: DNA binding domain, putative; SAND domain-like; Transcription regulator SKI/SnoN; Transforming protein Ski; c-SKI SMAD4-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, in adult female stages.
Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)