Gene Page - CG Number : CG11110

Gene Summary - CG11110:

CG11110: This gene is referred to in FlyBase by the symbol Dmel\CG11110 (FBgn0034535). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: serine-type peptidase activity. Based on sequence similarity, it is predicted to be involved in the biological process: protein processing involved in protein targeting to mitochondrion. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Mitochondrial inner membrane protease subunit 2; Peptidase S24/S26A/S26B; Peptidase S24/S26A/S26B/S26C; Peptidase S24/S26A/S26B/S26C, beta-ribbon domain; Peptidase S26A, signal peptidase I. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed in adult male stages.

Gene summary for CG11110 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)

Experimental Summary - CG11110:

CG11110 is not perturbed in primary screen.
CG11110 is not tested in classification assay.

Cellular phenotyping(Images):

Click here to access phenotyping images of gene CG11110.

Cell Count:

CG_Number	Category	R1	R2	R3
CG11110	Primary screen	686	755	436

R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3

Primary screen data - CG11110:

SN	RN	WN	Fint1	Fint2	Fint3	Fint4	Fnum	Fmph1	Fmph2	Fmph3	Fclc	Tint1	Tint2	Tint3	Tint4	Rto1	Rto2	Rto3	Okt	Tnum	Tmph1	Tmph2	Tmph3	Tclc	CellSize
20	1	239	-0.769375083	-0.200123739	0.621539786	0.075654977	0.73751613	-0.826860905	-0.869273299	-0.525046223	-0.047008882	0.807326576	-0.60107516	-0.083678221	-0.369268516	-0.285423621	2.687785038	0.745420679	-0.650791843	0.274430713	0.475847672	-0.933191305	-0.631294301	-0.550132209	-0.487772585
20	2	77	1.494946492	0.219226538	-0.111834515	0.076758836	1.306866449	0.885163352	0.246159728	1.286625925	1.719627591	0.172684147	0.92783549	0.02389277	0.873172549	0.368232856	0.980187343	0.593980895	0.175311288	0.509352541	0.188043301	1.203635511	0.665285191	9.99357032	2.818328784
20	3	227	-0.747404965	0.018443217	0.494311563	1.866723615	-0.791222682	0.613027496	0.66268523	0.617741467	-0.576425808	-0.013457714	-0.903871765	-0.785484571	-0.105283654	0.2717762	-0.528196521	-0.203912411	-1.027128216	-1.734631977	-0.032852626	-0.687787578	4.027031505	2.979473424	0.489302589

SN: Slide Number; RN: Replicate Number; WN: Well Number

Experimental Data (Classification Assay):

CG11110 is not tested in classification assay

Integrated Annotations for CG11110 :

Gene Ontology Annoations: Biological Process

Biological Process - Term	GO ID	Evidence
protein processing involved in protein targeting to mitochondrion	GO:0006627	inferred from sequence or structural similarity with SGD_LOCUS:IMP2; SGD:S0004638 proteolysis

Gene Ontology Annoations: Cellular Component

Cellular Component - Term	GO ID	Evidence
mitochondrial inner membrane	GO:0005743	inferred from sequence or structural similarity with SGD_LOCUS:IMP2; SGD:S0004638

Gene Ontology Annoations: Molecular Function

Molecular Function - Term	GO ID	Evidence
serine-type peptidase activity	GO:0008236	inferred from electronic annotation with InterPro:IPR000223

Other annotations

Database	Link
FlyBase	Click here to see CG11110 in FlyBase
FLIGHT	Click here to see CG11110 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRID	Click here to see CG11110 in BioGRID (Interaction Summary)
Off-target	Click here for Off-target data for CG11110
Entrez Gene	Entrez Gene page for CG11110
Uniprot	Uniprot page for CG11110

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Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)