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Gene Page - CG Number : CG11111
Gene Summary - CG11111:

CG11111: The gene retinal degeneration B is referred to in FlyBase by the symbol Dmel\rdgB (CG11111, FBgn0003218). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: phosphatidylcholine transporter activity; phosphatidylinositol transporter activity. There is experimental evidence that it is involved in the biological process: rhodopsin mediated signaling pathway; phototransduction; phosphatidylinositol metabolic process; deactivation of rhodopsin mediated signaling; sensory perception of smell. 49 alleles are reported. The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; organ system; histaminergic neuron; adult segment; rhabdomere R7; cell part; rhabdomere; cell projection. It has 10 annotated transcripts and 10 annotated polypeptides. Protein features are: DDHD; HAD-like domain; LNS2, Lipin/Ned1/Smp2; Phosphatidylinositol transfer protein; START-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.

Gene summary for CG11111 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11111:CG11111 is not perturbed in primary screen.
CG11111 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11111.
Cell Count:
CG_NumberCategoryR1R2R3
CG11111Primary screen670290553
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11111:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2012400.079074119-0.712229681-0.40667187-0.1122362330.431275723-0.567819242-0.294071247-0.164850409-0.135522285-0.236158811-0.33075581-0.115546393-0.281182991-0.4670135540.9048407620.559667463-0.2756615221.269789835-0.952486231-0.517208798-0.0449807621.5596650910.978085397
202760.3553317-0.009972008-0.011827399-0.608370793-1.330238408-0.511402194-0.870176215-0.526968556-0.5988253531.0852169341.880703320.1323517723.028323146-0.1835934191.627774434-0.225052742-0.0401696771.2942436231.0364430420.1771702640.4268067530.610044412-0.789388263
203226-0.744637886-0.420009811-0.448969679-0.576148783-0.268749368-1.293847366-1.697714371-1.816982394-2.483016733-0.429315633-0.337949955-0.3969348920.0250369020.8020503780.068798701-0.066712244-0.448090771-1.6681450122.231713064-3.8445035871.4881780511.72897415-0.110246644
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11111 is not tested in classification assay
Integrated Annotations for CG11111 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
sensory perception of smellGO:0007608inferred from mutant phenotype
phototransduction
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to plasma membraneGO:0005887inferred from sequence or structural similarity
plasma membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
calcium-transporting ATPase activityGO:0005388inferred from sequence or structural similarity
phosphatidylinositol transporter activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11111 in FlyBase
FLIGHTClick here to see CG11111 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11111 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11111
Entrez GeneEntrez Gene page for CG11111
UniprotUniprot page for CG11111

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)