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Gene Page - CG Number : CG11115
Gene Summary - CG11115:

CG11115: The gene Ssl1 is referred to in FlyBase by the symbol Dmel\Ssl1 (CG11115, FBgn0037202). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding. There is experimental evidence that it is involved in the biological process: transcription from RNA polymerase II promoter. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Ssl1-like; TFIIH C1-like domain; TFIIH basal transcription factor complex, subunit SSL1; Zinc finger, C2H2; von Willebrand factor, type A. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages.

Gene summary for CG11115 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11115:CG11115 is not perturbed in primary screen.
CG11115 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11115.
Cell Count:
CG_NumberCategoryR1R2R3
CG11115Primary screen357610416
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11115:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201242-1.00131107-0.132307909-0.093374884-0.356571609-0.478643994-1.942925079-0.73386216-1.52511-1.4467338580.045252261-0.332892951-0.839539874-0.0092760570.278126808-0.528234568-1.1867060561.827593089-1.3116267220.824181988-1.575300761-0.4686482070.371802875-0.814378556
20244-0.58678793-0.551777027-0.448757203-0.1163199980.7745694391.6097238640.9611395611.5807637362.0453988590.4090997350.5368824850.3950022860.031890160.384134581-0.985773080.526733940.1650931641.8416995590.2723107981.909239891.2874825985.0266881791.144259433
203194-0.952969737-0.409762521-0.458500537-0.622399681-0.2074767661.0031902840.5983601290.9333828330.658013307-0.302578835-0.299372013-0.698515538-0.584094003-0.437787635-0.038381741-0.1175876571.607973403-0.1778881592.8743198021.1263729063.7749123810.51970742-0.279229842
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11115 is not tested in classification assay
Integrated Annotations for CG11115 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
transcription initiation from RNA polymerase II promoterGO:0006367inferred from sequence or structural similarity with HGNC_gene:GTF2H2; HGNC:4656; OMIM:601748 AND inferred from sequence or structural similarity with SGD_LOCUS:SSL1; SGD:S0003995
nucleotide-excision repair
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
holo TFIIH complexGO:0005675inferred from sequence or structural similarity with HGNC_gene:GTF2H2; HGNC:4656; OMIM:601748 AND inferred from sequence or structural similarity with SGD_LOCUS:SSL1; SGD:S0003995
core TFIIH complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
zinc ion bindingGO:0008270inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR007198, InterPro:IPR012170
Other annotations
DatabaseLink
FlyBaseClick here to see CG11115 in FlyBase
FLIGHTClick here to see CG11115 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11115 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11115
Entrez GeneEntrez Gene page for CG11115
UniprotUniprot page for CG11115

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)