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Gene Page - CG Number : CG1112
Gene Summary - CG1112:

CG1112: The gene α-Esterase-7 is referred to in FlyBase by the symbol Dmel\α-Est7 (CG1112, FBgn0015575). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: carboxylesterase activity. There is experimental evidence that it is involved in the biological process: response to organophosphorus; determination of adult lifespan; lipid storage. 11 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Carboxylesterase type B, active site; Carboxylesterase, type B. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed at stages throughout the larval period, in adult male stages.

Gene summary for CG1112 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1112:CG1112 is not perturbed in primary screen.
CG1112 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1112.
Cell Count:
CG_NumberCategoryR1R2R3
CG1112Primary screen753764320
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1112:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG1112 is not tested in classification assay
Integrated Annotations for CG1112 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
biological_processGO:0008150no biological data available
determination of adult lifespan
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
lipid particleGO:0005811inferred from direct assay
cytoplasm
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
carboxylesterase activityGO:0004091non-traceable author statement
carboxylesterase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG1112 in FlyBase
FLIGHTClick here to see CG1112 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1112 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1112
Entrez GeneEntrez Gene page for CG1112
UniprotUniprot page for CG1112

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)