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Gene Page - CG Number : CG11132
Gene Summary - CG11132:

CG11132: The gene DMAP1 is referred to in FlyBase by the symbol Dmel\DMAP1 (CG11132, FBgn0034537). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: chromatin binding. There is experimental evidence that it is involved in the biological process: phagocytosis, engulfment. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: DNA methyltransferase 1-associated 1; SANT/Myb domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG11132 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11132:CG11132 is perturbed in following parameters in primary screen: Fint2 Fint3
CG11132 is perturbed in following parameters in classification assay (fluid): CellSize+(fld) LP_Fclc- NuSize-(fld) Rto1+ Rto2+ Rto3+ SP_Fclc- SP_Fint2+ SP_Fint3+ SP_Fmph1- SP_Fmph2- SP_Fmph3- SP_Fnum-
CG11132 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11132.
Cell Count:
CG_NumberCategoryR1R2R3
CG11132Primary screen403456298
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11132:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2012461.2017330274.7946509493.388496693-0.922481772-0.558807598-0.9923939051.650860637-0.6782484130.5926164810.1592203970.2125447170.2047976680.470516995-0.284092480.690104822-0.2663077080.3082503671.440306350.4835126251.242116867-0.581345424-0.2501047170.518233316
202405.8014991258.0296978814.417300425-0.0225253790.3986254564.4835315895.1724712284.0176398183.0516787071.5878726410.3016557510.9234579670.6872069471.1292477722.376435057-0.429050562.6124283493.07088020.5076311634.214230419-0.2603035270.901223322-0.432060696
2031902.138992635.8864170793.075070644-0.21634571-1.521578442-2.04498641-0.974007734-3.062555385-0.870704872-1.087021268-1.051495589-0.280124241.297625008-0.331586752-0.8430613850.059980765-0.612609219-0.343852899-1.017611159-1.6361129481.5571297950.2318768880.588824389
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11132Slide4C0.4411.0321.0781.189
CG11132Slide4O0.2430.9511.5731.377
CG11132Slide4P0.0211.4211.1861.369
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11132 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
phagocytosis, engulfmentGO:0006911inferred from mutant phenotype
negative regulation of transcription, DNA-dependent
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
NuA4 histone acetyltransferase complexGO:0035267colocalizes_with inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
DNA bindingGO:0003677inferred from electronic annotation with InterPro:IPR001005
Other annotations
DatabaseLink
FlyBaseClick here to see CG11132 in FlyBase
FLIGHTClick here to see CG11132 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11132 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11132
Entrez GeneEntrez Gene page for CG11132
UniprotUniprot page for CG11132

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)