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Gene Page - CG Number : CG11136
Gene Summary - CG11136:

CG11136: The gene Leucine-rich tendon-specific protein is referred to in FlyBase by the symbol Dmel\Lrt (CG11136, FBgn0034540). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: negative regulation of muscle cell chemotaxis toward tendon cell; Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell. 9 alleles are reported. The phenotypes of these alleles are annotated with: A1-7 ventral oblique muscle 4; A1-7 ventral acute muscle 3; embryonic/larval somatic muscle; ventral longitudinal muscle. It has one annotated transcript and one annotated polypeptide. Protein features are: Cysteine-rich flanking region, C-terminal; Leucine-rich repeat; Leucine-rich repeat, typical subtype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis.

Gene summary for CG11136 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11136:CG11136 is not perturbed in primary screen.
CG11136 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11136.
Cell Count:
CG_NumberCategoryR1R2R3
CG11136Primary screen603983565
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11136:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201248-0.433539529-0.902911954-0.8903458930.2735014340.2603684770.134625733-0.3645838150.11382523-0.086537208-0.436171928-0.5026482180.448284712-0.621384478-0.2036986370.6077867570.5000059480.407466301-0.746846347-0.2671846810.335829461-0.7228037920.882272492-0.128164838
20238-0.2213028430.2519844420.089303936-0.0042918422.6824966141.8397501331.1761511912.111546482.596625870.7313039990.497702599-0.4279625195.5123812173.2349160263.6089771141.30926241-0.115193819-0.14325554-1.108395321.9131920281.60962141610.031607244.465237703
203188-0.4504364530.7333401720.802224116-0.3373963020.6084709021.6652034980.4250397421.883256360.406425774-0.25248681-0.8630764690.863495606-0.0175810661.393012848-0.4596529730.746633671-0.543904558-0.288813835-1.1321214670.4575899370.9929282560.222236905-0.478060233
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11136 is not tested in classification assay
Integrated Annotations for CG11136 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cellGO:2001283inferred from genetic interaction with robo
negative regulation of muscle cell chemotaxis toward tendon cell
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
muscle tendon junctionGO:0005927inferred from direct assay
plasma membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein bindingGO:0005515inferred from physical interaction with robo
Other annotations
DatabaseLink
FlyBaseClick here to see CG11136 in FlyBase
FLIGHTClick here to see CG11136 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11136 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11136
Entrez GeneEntrez Gene page for CG11136
UniprotUniprot page for CG11136

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)