.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG11136Gene Summary - CG11136:CG11136: The gene Leucine-rich tendon-specific protein is referred to in FlyBase by the symbol Dmel\Lrt (CG11136, FBgn0034540). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: negative regulation of muscle cell chemotaxis toward tendon cell; Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell. 9 alleles are reported. The phenotypes of these alleles are annotated with: A1-7 ventral oblique muscle 4; A1-7 ventral acute muscle 3; embryonic/larval somatic muscle; ventral longitudinal muscle. It has one annotated transcript and one annotated polypeptide. Protein features are: Cysteine-rich flanking region, C-terminal; Leucine-rich repeat; Leucine-rich repeat, typical subtype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis. Gene summary for CG11136 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG11136:CG11136 is not perturbed in primary screen. CG11136 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11136.Cell Count:CG_NumberCategoryR1R2R3CG11136Primary screen603983565R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG11136: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize201248-0.433539529-0.902911954-0.8903458930.2735014340.2603684770.134625733-0.3645838150.11382523-0.086537208-0.436171928-0.5026482180.448284712-0.621384478-0.2036986370.6077867570.5000059480.407466301-0.746846347-0.2671846810.335829461-0.7228037920.882272492-0.12816483820238-0.2213028430.2519844420.089303936-0.0042918422.6824966141.8397501331.1761511912.111546482.596625870.7313039990.497702599-0.4279625195.5123812173.2349160263.6089771141.30926241-0.115193819-0.14325554-1.108395321.9131920281.60962141610.031607244.465237703203188-0.4504364530.7333401720.802224116-0.3373963020.6084709021.6652034980.4250397421.883256360.406425774-0.25248681-0.8630764690.863495606-0.0175810661.393012848-0.4596529730.746633671-0.543904558-0.288813835-1.1321214670.4575899370.9929282560.222236905-0.478060233 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG11136 is not tested in classification assayIntegrated Annotations for CG11136 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidenceRoundabout signaling pathway involved in muscle cell chemotaxis toward tendon cellGO:2001283inferred from genetic interaction with robo negative regulation of muscle cell chemotaxis toward tendon cellGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidencemuscle tendon junctionGO:0005927inferred from direct assay plasma membraneGene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidenceprotein bindingGO:0005515inferred from physical interaction with robo Other annotations DatabaseLinkFlyBaseClick here to see CG11136 in FlyBaseFLIGHTClick here to see CG11136 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG11136 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG11136Entrez GeneEntrez Gene page for CG11136UniprotUniprot page for CG11136 Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)
.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG11136Gene Summary - CG11136:CG11136: The gene Leucine-rich tendon-specific protein is referred to in FlyBase by the symbol Dmel\Lrt (CG11136, FBgn0034540). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: negative regulation of muscle cell chemotaxis toward tendon cell; Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell. 9 alleles are reported. The phenotypes of these alleles are annotated with: A1-7 ventral oblique muscle 4; A1-7 ventral acute muscle 3; embryonic/larval somatic muscle; ventral longitudinal muscle. It has one annotated transcript and one annotated polypeptide. Protein features are: Cysteine-rich flanking region, C-terminal; Leucine-rich repeat; Leucine-rich repeat, typical subtype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis. Gene summary for CG11136 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG11136:CG11136 is not perturbed in primary screen. CG11136 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11136.Cell Count:CG_NumberCategoryR1R2R3CG11136Primary screen603983565R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG11136: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize201248-0.433539529-0.902911954-0.8903458930.2735014340.2603684770.134625733-0.3645838150.11382523-0.086537208-0.436171928-0.5026482180.448284712-0.621384478-0.2036986370.6077867570.5000059480.407466301-0.746846347-0.2671846810.335829461-0.7228037920.882272492-0.12816483820238-0.2213028430.2519844420.089303936-0.0042918422.6824966141.8397501331.1761511912.111546482.596625870.7313039990.497702599-0.4279625195.5123812173.2349160263.6089771141.30926241-0.115193819-0.14325554-1.108395321.9131920281.60962141610.031607244.465237703203188-0.4504364530.7333401720.802224116-0.3373963020.6084709021.6652034980.4250397421.883256360.406425774-0.25248681-0.8630764690.863495606-0.0175810661.393012848-0.4596529730.746633671-0.543904558-0.288813835-1.1321214670.4575899370.9929282560.222236905-0.478060233 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG11136 is not tested in classification assayIntegrated Annotations for CG11136 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidenceRoundabout signaling pathway involved in muscle cell chemotaxis toward tendon cellGO:2001283inferred from genetic interaction with robo negative regulation of muscle cell chemotaxis toward tendon cellGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidencemuscle tendon junctionGO:0005927inferred from direct assay plasma membraneGene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidenceprotein bindingGO:0005515inferred from physical interaction with robo Other annotations DatabaseLinkFlyBaseClick here to see CG11136 in FlyBaseFLIGHTClick here to see CG11136 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG11136 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG11136Entrez GeneEntrez Gene page for CG11136UniprotUniprot page for CG11136
CG11136: The gene Leucine-rich tendon-specific protein is referred to in FlyBase by the symbol Dmel\Lrt (CG11136, FBgn0034540). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: negative regulation of muscle cell chemotaxis toward tendon cell; Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell. 9 alleles are reported. The phenotypes of these alleles are annotated with: A1-7 ventral oblique muscle 4; A1-7 ventral acute muscle 3; embryonic/larval somatic muscle; ventral longitudinal muscle. It has one annotated transcript and one annotated polypeptide. Protein features are: Cysteine-rich flanking region, C-terminal; Leucine-rich repeat; Leucine-rich repeat, typical subtype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis.
Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)