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Gene Page - CG Number : CG11140
Gene Summary - CG11140:

CG11140: The gene Aldehyde dehydrogenase type III is referred to in FlyBase by the symbol Dmel\Aldh-III (CG11140, FBgn0010548). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process; cellular aldehyde metabolic process. 12 alleles are reported. The phenotype of these alleles is annotated with: crystal cell. It has 13 annotated transcripts and 13 annotated polypeptides. Protein features are: Aldehyde dehydrogenase NAD(P)-dependent; Aldehyde dehydrogenase domain; Aldehyde dehydrogenase, C-terminal; Aldehyde dehydrogenase, N-terminal; Aldehyde dehydrogenase, conserved site; Aldehyde/histidinol dehydrogenase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during early pupal stages, in adult male stages.

Gene summary for CG11140 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11140:CG11140 is not perturbed in primary screen.
CG11140 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11140.
Cell Count:
CG_NumberCategoryR1R2R3
CG11140Primary screen433303672
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11140:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2012520.689152664-0.596633546-0.9149727270.095716809-0.480318602-1.1441567-0.969326552-0.786531655-1.2521505930.17850847-0.2617509860.3767512610.77738333-0.8670951730.131394656-0.0064383910.0479303840.1585198990.932701226-0.4115784730.0846529260.6569217130.162024242
202340.164158515-0.686076887-0.360248275-0.153068423-0.8247139740.2427530451.695338456-0.0215712770.003189047-0.197757227-0.645554646-0.48132015-0.2628986471.9147760760.451305941-0.835914974-0.5731756621.001321694-0.6836620640.454691232-0.3936320840.259733028-0.572244151
2031840.111517374-0.511478662-0.5916826250.3850214690.8862649511.8178128040.8612513391.9279740952.823221039-0.0261151062.5860237060.6792756171.5792721412.1472070120.5800556120.7397475512.2392560783.6148601092.5593750143.3043343820.2415446886.2507134722.804643339
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11140 is not tested in classification assay
Integrated Annotations for CG11140 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
oxidation-reduction processGO:0055114inferred from electronic annotation with InterPro:IPR012394, InterPro:IPR015590, InterPro:IPR016160, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163
cellular aldehyde metabolic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
lipid particleGO:0005811inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptorGO:0016620inferred from sequence or structural similarity with MGD:Aldh3a1; MGI:MGI:1353451
aldehyde dehydrogenase [NAD(P)+] activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11140 in FlyBase
FLIGHTClick here to see CG11140 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11140 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11140
Entrez GeneEntrez Gene page for CG11140
UniprotUniprot page for CG11140

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)