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Gene Page - CG Number : CG11154
Gene Summary - CG11154:

CG11154: The gene ATP synthase-β is referred to in FlyBase by the symbol Dmel\ATPsyn-β (CG11154, FBgn0010217). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: hydrogen-exporting ATPase activity, phosphorylative mechanism. There is experimental evidence that it is involved in the biological process: lateral inhibition. 10 alleles are reported. The phenotypes of these alleles are annotated with: adult thorax; chaeta; wing. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: AAA+ ATPase domain; ATPase, F1 complex beta subunit/V1 complex, C-terminal; ATPase, F1 complex, beta subunit; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, alpha/beta subunit, N-terminal; ATPase, alpha/beta subunit, nucleotide-binding domain, active site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.

Gene summary for CG11154 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11154:CG11154 is not perturbed in primary screen.
CG11154 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11154.
Cell Count:
CG_NumberCategoryR1R2R3
CG11154Primary screen326323386
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11154:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2012650.2566828730.1492081121.3036195010.052501045-0.619478919-1.8688948180.431072812-1.390946084-1.203266386-1.182802290.0850684-0.410417617-0.241798078-0.895483341-0.043565661-1.033308502-0.6874601780.7794593060.220714014-0.67546335-0.371349426-0.722008212-0.500061612
20251-0.441128534-0.181862878-0.0263643371.040336316-0.2658872051.5530598940.887886820.8867131030.5653533830.341659723-0.586730767-0.8185730121.1355933370.9942180181.307046369-0.598954921-0.2556623641.8466627060.4599054260.550088383-0.21520357-0.204629159-0.458086183
203201-0.5513501-0.048050528-0.00835174-0.156954134-0.7932939641.0317909771.4708818370.8670355921.191313037-1.347426971-0.6376269320.968650080.0441503550.091052747-0.184820347-0.083816572-0.690948799-0.22835078-0.0230017852.4894819281.4020152461.208359595-0.167559289
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11154 is not tested in classification assay
Integrated Annotations for CG11154 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
proton transportGO:0015992non-traceable author statement
proton transport
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)GO:0000275inferred from sequence or structural similarity with UniProtKB:P06576
lipid particle
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
hydrogen-exporting ATPase activity, phosphorylative mechanismGO:0008553inferred from sequence or structural similarity with UniProtKB:Q9PTY0
hydrogen-exporting ATPase activity, phosphorylative mechanism
Other annotations
DatabaseLink
FlyBaseClick here to see CG11154 in FlyBase
FLIGHTClick here to see CG11154 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11154 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11154
Entrez GeneEntrez Gene page for CG11154
UniprotUniprot page for CG11154

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)