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Gene Page - CG Number : CG11172
Gene Summary - CG11172:

CG11172: The gene NFAT homolog is referred to in FlyBase by the symbol Dmel\NFAT (CG11172, FBgn0030505). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity. There is experimental evidence that it is involved in the biological process: negative regulation of synaptic vesicle exocytosis; negative regulation of Ras protein signal transduction; response to salt stress; regulation of response to DNA damage stimulus; imaginal disc-derived wing morphogenesis. 50 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system subdivision; organ system; adult segment; embryonic/larval neuron; synapse; multicellular structure; peripheral nervous system; thoracic segment; adult; eo support cell; embryonic/larval anal pad; external compound sense organ. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Armadillo-like helical; Cell surface receptor IPT/TIG; Immunoglobulin E-set; Immunoglobulin-like fold; Nuclear factor of activated T cells (NFAT); Rel homology; p53-like transcription factor, DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.

Gene summary for CG11172 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11172:CG11172 is not perturbed in primary screen.
CG11172 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11172.
Cell Count:
CG_NumberCategoryR1R2R3
CG11172Primary screen467594489
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11172:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201271-0.0567752761.4686978310.714212796-0.854610996-0.1542431250.286723791.219985236-0.0707048710.0281304690.756592335-0.3276874273.088998238-0.168933525-0.504824721-0.372904806-0.276557662-0.566933968-0.7784407150.2428345280.788062291-0.0035501381.7610941180.800075625
20215-0.3200118070.106566923-0.045489581-0.485812910.5992985691.6376719211.4074640151.7707634771.3327813320.36051059-0.352431347-0.397819198-0.6947599930.06297540.2786905281.279409529-0.978662279-0.302269804-0.3228037251.220074359-0.3060087492.4253177410.81787421
203165-0.5129235850.085912078-0.6095075580.1972828940.4228721781.014910846-0.3645018961.138542683-0.19461217-0.131715367-0.4304740310.4162206-0.795956962-0.910053292-0.566204482-0.059908701-0.3487945160.2349068871.637556362-0.7986081240.2978271771.1759582640.118131407
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11172 is not tested in classification assay
Integrated Annotations for CG11172 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
response to salt stressGO:0009651inferred from mutant phenotype
transcription, DNA-dependent
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from sequence or structural similarity
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA binding transcription factor activityGO:0003700inferred from sequence or structural similarity
sequence-specific DNA binding transcription factor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11172 in FlyBase
FLIGHTClick here to see CG11172 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11172 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11172
Entrez GeneEntrez Gene page for CG11172
UniprotUniprot page for CG11172

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)