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Gene Page - CG Number : CG11183
Gene Summary - CG11183:

CG11183: The gene Decapping protein 1 is referred to in FlyBase by the symbol Dmel\Dcp1 (CG11183, FBgn0034921). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: nuclear-transcribed mRNA catabolic process; positive regulation of gene silencing by miRNA; regulation of cytoplasmic mRNA processing body assembly; pole plasm oskar mRNA localization; gene silencing by miRNA. 17 alleles are reported. The phenotype of these alleles is annotated with: cytoplasmic mRNA processing body. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Dcp1-like decapping. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.

Gene summary for CG11183 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11183:CG11183 is not perturbed in primary screen.
CG11183 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11183.
Cell Count:
CG_NumberCategoryR1R2R3
CG11183Primary screen319633519
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11183:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201277-0.9688593670.529863836-0.1684705430.387662088-0.874847327-1.913500213-1.106984664-1.41523863-1.510543768-0.19792297-0.6393838730.233547249-0.025416389-0.9513519940.114917356-1.673380228-0.906500902-0.840354098-0.024036419-1.880084729-0.663811778-0.808845627-0.762313112
2029-0.0611141850.1851337260.358019912-0.3658051281.0599841211.076787250.4744825991.354027290.552013961.270513417-0.3864050750.7300212080.829508857-0.5501967671.7556086950.669401426-1.646553282-0.101750118-0.8647663660.1355453750.3154581710.183621706-0.254924082
203159-0.424226193-0.142209394-0.389416567-0.1865217030.3396031251.3363624680.24943511.2931762560.6294434180.05597464-0.4585357467.75931315910.6173774111.66464176-0.1809072280.1282678360.187059949-0.5951707740.0732025260.6451986940.138007727-0.153691659-0.121823343
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11183 is not tested in classification assay
Integrated Annotations for CG11183 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
nuclear-transcribed mRNA catabolic process, nonsense-mediated decayGO:0000184NOT inferred from mutant phenotype
gene silencing by miRNA
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
P granuleGO:0043186inferred from direct assay
cytoplasmic mRNA processing body
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
m7G(5')pppN diphosphatase activityGO:0050072NOT inferred from direct assay
Other annotations
DatabaseLink
FlyBaseClick here to see CG11183 in FlyBase
FLIGHTClick here to see CG11183 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11183 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11183
Entrez GeneEntrez Gene page for CG11183
UniprotUniprot page for CG11183

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)