Home Browse SearchHelp DownloadGroup

.:: RNAiDB - Gene Page ::.
Gene Page - CG Number : CG11194
Gene Summary - CG11194:

CG11194: The gene Hairy/E(spl)-related with YRPW motif is referred to in FlyBase by the symbol Dmel\Hey (CG11194, FBgn0027788). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity; DNA binding. Based on sequence similarity, it is predicted to be involved in the biological process: negative regulation of Notch signaling pathway. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Helix-loop-helix domain; Orange; Orange subgroup. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-18 hour embryonic stages.

Gene summary for CG11194 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11194:CG11194 is perturbed in following parameters in primary screen: Tint2 Tint3 Tint4 Tmph1 Tmph2 Tmph3
CG11194 is not tested in classification assay (fluid).
CG11194 is perturbed in following parameters in classification assay (transferrin): Fclc- Fint1- Fint2- Fint4- Fmph1- Fmph2- Fmph3- Fnum- Okt+(tfr) Rto1-(tfr) Tclc- Tnum-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11194.
Cell Count:
CG_NumberCategoryR1R2R3
CG11194Primary screen357427581
CG11194Secondary assay727876982
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11194:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201282-0.415228114-0.0996062390.783361724-0.754395094-0.796548833-1.25544898-2.579419183-1.9244300811.1800479055.0254664492.78340191.31070825-0.44986750.3976550792.722233177-0.8197826373.149724767.2301389054.693079710.177325143-0.174723473-0.0196314812.904679846
20241.676094968-0.173358415-0.434066864-0.5560286440.019002050.8758632320.5031552451.2424249492.0405434773.8086237054.781796263-0.219977620.1896022950.6109174760.9184772330.3611042513.8932674026.9024830483.39976152.823577754-0.187172076-0.7248785880.552654914
2031540.599269798-0.3612384140.659798412-0.0755275640.7499536862.1495753411.0601701011.7627616783.7134347582.4206081783.739054701-0.1917925920.3651239170.1637233592.368578230.6692483636.80776454110.569020339.5879671065.180889202-0.486205625.2898608412.846244056
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11194Slide2F0.0020.4970.6690.598
CG11194Slide2O0.0021.4981.3671.360
CG11194Slide2T0.0720.5740.8290.344
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG11194 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
negative regulation of Notch signaling pathwayGO:0045746inferred from sequence or structural similarity with UniProtKB:Q9QUS4
regulation of transcription, DNA-dependent
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from sequence or structural similarity with EMBL:AF151521; protein_id:AAD38966.1
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA binding transcription factor activityGO:0003700inferred from sequence or structural similarity with EMBL:AF151521; protein_id:AAD38966.1
DNA binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11194 in FlyBase
FLIGHTClick here to see CG11194 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11194 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11194
Entrez GeneEntrez Gene page for CG11194
UniprotUniprot page for CG11194

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)