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Gene Page - CG Number : CG11199
Gene Summary - CG11199:

CG11199: The gene Liprin-α is referred to in FlyBase by the symbol Dmel\Liprin-α (CG11199, FBgn0046704). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: R7 cell development; synapse assembly; regulation of axon extension involved in axon guidance; axon guidance; axon extension involved in development; anterograde synaptic vesicle transport; synaptic growth at neuromuscular junction; retinal ganglion cell axon guidance; axon target recognition; photoreceptor cell morphogenesis. 26 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor cell R7; medulla; bouton; neuromuscular junction; synaptic vesicle. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Sterile alpha motif domain; Sterile alpha motif, type 1; Sterile alpha motif, type 2; Sterile alpha motif/pointed domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in adult female stages.

Gene summary for CG11199 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11199:CG11199 is not perturbed in primary screen.
CG11199 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11199.
Cell Count:
CG_NumberCategoryR1R2R3
CG11199Primary screen357745428
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11199:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2012851.222166983-0.300709495-0.418465641-0.563933397-1.267069838-7.776822928-3.486066888-6.18229379-4.0430121050.523347275-0.505872473-0.510854984-0.450668204-1.035282285-0.549179145-0.062773717-0.855700927-0.9456286842.563193397-4.669758678-0.412443946-0.8580022-0.018150044
20211.8463937530.403602074-0.2677075860.2842899922.5045698991.3100887370.6286425141.3020520531.259214241-0.790625142-0.406242135-0.0584708861.5279530770.4952683471.1937280372.005231163-0.424709322-0.4910292791.6759483620.9929102911.2654857454.5736858362.518899778
203151-0.880053059-0.299403397-0.245885273-0.5922627370.6525487490.46931727-0.5065495520.5130953280.441739526-0.8521346990.647484479-0.561815726-0.5530010230.3989174810.8235460450.0074626490.322700627-0.5130484430.5034120580.3754588330.1313963951.6031284530.587509074
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11199 is not tested in classification assay
Integrated Annotations for CG11199 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
photoreceptor cell morphogenesisGO:0008594inferred from mutant phenotype
synapse assembly
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
synapseGO:0045202inferred from direct assay
protein complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein bindingGO:0005515inferred from physical interaction with Liprin-β inferred from physical interaction with Liprin-γ
Other annotations
DatabaseLink
FlyBaseClick here to see CG11199 in FlyBase
FLIGHTClick here to see CG11199 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11199 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11199
Entrez GeneEntrez Gene page for CG11199
UniprotUniprot page for CG11199

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)