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Gene Page - CG Number : CG11242
Gene Summary - CG11242:

CG11242: The gene tubulin-binding cofactor B is referred to in FlyBase by the symbol Dmel\TBCB (CG11242, FBgn0034451). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: oocyte axis specification; establishment of apical/basal cell polarity; cytoplasmic microtubule organization. 8 alleles are reported. The phenotype of these alleles is annotated with: wing. It has one annotated transcript and one annotated polypeptide. Protein features are: CAP Gly-rich domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG11242 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11242:CG11242 is perturbed in following parameters in primary screen: NuSize
CG11242 is perturbed in following parameters in classification assay (fluid): CellSize+(fld) LP_Fint1+ LP_Fmph1+ Rto2+ Rto3+ SP_Fint1+ SP_Fint2+ SP_Fint3+
CG11242 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11242.
Cell Count:
CG_NumberCategoryR1R2R3
CG11242Primary screen892721706
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11242:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
21122.0444956360.5083217560.100323187-0.3323662471.5208950132.1884672321.2726717861.9234710992.891835787-0.0255753920.7565676010.012472556-0.1367141950.4788381.7632361371.55227993-0.054378509-0.021954158-0.1031461472.5635591610.8589960234.8393795135.727319943
2121642.578909242-0.212976114-0.3654541580.267209091.6923454861.395908651.0145342821.6546663181.6141769651.0131656670.11604751.3967652840.5518468240.8701846912.0769331310.327648938-0.583144082-0.040953444-0.5087171931.279087802-0.145334558.40467782.517093659
213134-0.156752436-0.064671099-0.0834469370.1238186040.4078011332.3630163171.2878064452.4783984163.0054873820.0907140730.997329369-0.6951132020.4097560211.055743617-0.3194872121.4454470581.1752826955.0937783542.5389506563.320693402-0.6702465474.6415020712.79438729
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11242Slide8C0.2611.3121.0671.030
CG11242Slide8O0.2511.2091.1430.976
CG11242Slide8P0.0491.3541.2331.115
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11242 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
-
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoskeletonGO:0005856inferred from sequence or structural similarity with UniProtKB:Q99426
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
-
Other annotations
DatabaseLink
FlyBaseClick here to see CG11242 in FlyBase
FLIGHTClick here to see CG11242 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11242 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11242
Entrez GeneEntrez Gene page for CG11242
UniprotUniprot page for CG11242

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)