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Gene Page - CG Number : CG11259
Gene Summary - CG11259:

CG11259: The gene MICAL-like is referred to in FlyBase by the symbol Dmel\MICAL-like (CG11259, FBgn0036333). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: actin binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Calponin homology domain; Domain of unknown function DUF3585; Zinc finger, LIM-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.

Gene summary for CG11259 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11259:CG11259 is perturbed in following parameters in primary screen: NuCirc NuFluct NuSize
CG11259 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11259.
Cell Count:
CG_NumberCategoryR1R2R3
CG11259Primary screen935355241
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11259:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211141.04055187-0.352159062-0.3518438990.7269227360.411297508-0.28695497-0.2177268390.4017024320.38823157-0.3857630650.581243334-0.2202860550.410987559-0.0262278981.9565681841.643470180.864220965-0.0457759110.7758562071.0080140023.8142888445.8137487375.039996911
212152-0.218209645-0.2762427890.63693201-0.5138433450.034629270.9636631020.963288061.0667248080.743802759-0.3215496221.062537807-0.2615416111.3486341.1818849561.2315093970.078028825-0.2552733721.688260801-0.8113933540.998376157-0.4305133197.388720252.909817725
213122-0.663168412-0.6090961210.221090713-0.5349578310.319467318-2.229782494-2.819927518-2.971385559-1.244027402-0.935496907-0.7473576820.2850159642.9711755383.394199307-0.522857852-0.335730292.4143652620.002572753-1.446613368-2.885467503-0.0422112874.0196130718.5205283
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11259 is not tested in classification assay
Integrated Annotations for CG11259 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
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Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
actin bindingGO:0003779inferred from sequence or structural similarity
actin binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11259 in FlyBase
FLIGHTClick here to see CG11259 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11259 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11259
Entrez GeneEntrez Gene page for CG11259
UniprotUniprot page for CG11259

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)