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Gene Page - CG Number : CG11261
Gene Summary - CG11261:

CG11261: This gene is referred to in FlyBase by the symbol Dmel\CG11261 (FBgn0036332). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: ubiquitin protein ligase binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ubiquitin-dependent protein catabolic process. 5 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Cullin homology; Cullin protein, neddylation domain; Cullin repeat-like-containing domain; Cullin, N-terminal; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.

Gene summary for CG11261 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11261:CG11261 is perturbed in following parameters in primary screen: NuSize
CG11261 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11261.
Cell Count:
CG11261Primary screen724569510
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11261:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11261 is not tested in classification assay
Integrated Annotations for CG11261 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
ubiquitin-dependent protein catabolic processGO:0006511inferred from electronic annotation with InterPro:IPR001373, InterPro:IPR016158, InterPro:IPR019559
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nuclear ubiquitin ligase complexGO:0000152inferred from sequence or structural similarity with EMBL:AF083216; protein_id:AAD16038
cullin-RING ubiquitin ligase complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ubiquitin protein ligase bindingGO:0031625inferred from electronic annotation with InterPro:IPR001373, InterPro:IPR016158, InterPro:IPR019559
Other annotations
FlyBaseClick here to see CG11261 in FlyBase
FLIGHTClick here to see CG11261 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11261 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11261
Entrez GeneEntrez Gene page for CG11261
UniprotUniprot page for CG11261

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)