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Gene Page - CG Number : CG11276
Gene Summary - CG11276:

CG11276: The gene Ribosomal protein S4 is referred to in FlyBase by the symbol Dmel\RpS4 (CG11276, FBgn0011284). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process: centrosome organization; mitotic spindle elongation; mitotic spindle organization; centrosome duplication. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: KOW; RNA-binding S4 domain; Ribosomal protein S4e; Ribosomal protein S4e, N-terminal; Ribosomal protein S4e, N-terminal, conserved site; Ribosomal protein S4e, central. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.

Gene summary for CG11276 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11276:CG11276 is perturbed in following parameters in primary screen: Tmph1 Tmph2
CG11276 is not tested in classification assay (fluid).
CG11276 is perturbed in following parameters in classification assay (transferrin): Fint1+ Fmph1+ Fmph2+ Fmph3+ NuSize-(tfr) Rto1-(tfr) Tint1-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11276.
Cell Count:
CG_NumberCategoryR1R2R3
CG11276Primary screen506326625
CG11276Secondary assay869699654
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11276:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
21124-0.7358635151.8031265092.622578233-0.035448550.164381762-0.036460930.0212978920.0752485731.4771969051.242597407-0.233091593-0.366291559-0.7581983950.061719661.008642928-0.253836719-0.5119831971.684806828-0.509297781.7447203140.2378790732.2691881961.666006666
212172-0.58045361-0.3598127420.314852356-0.523747976-0.937397386-0.271631393-0.762151347-0.431626233-0.0040372872.6740779610.9748034340.7786971730.1180604330.0405421371.889857903-0.6686704863.3835841833.0585140050.629231118-0.568184764-0.1567635821.618276928-0.42587238
213142-0.048630148-0.626702124-0.5594838550.0108171530.7360058150.979795128-0.3663540130.5958070362.9889820330.7034889393.827736445-0.1359931850.6416698140.731580915-0.1563477180.0611417953.4994833886.7838237690.8143646322.45860292-0.6630218914.4122366763.040373386
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11276Slide10F0.0001.2631.3081.325
CG11276Slide10O0.1511.0311.1171.034
CG11276Slide10T0.3490.9921.0961.312
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG11276 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
translationGO:0006412non-traceable author statement
translation
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
ribosomeGO:0005840non-traceable author statement
lipid particle
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
structural constituent of ribosomeGO:0003735non-traceable author statement
structural constituent of ribosome
Other annotations
DatabaseLink
FlyBaseClick here to see CG11276 in FlyBase
FLIGHTClick here to see CG11276 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11276 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11276
Entrez GeneEntrez Gene page for CG11276
UniprotUniprot page for CG11276

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)