Gene Page - CG Number : CG11305

Gene Summary - CG11305:

CG11305: The gene Sirt7 is referred to in FlyBase by the symbol Dmel\Sirt7 (CG11305, FBgn0039631). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: NAD+ binding. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Sirtuin family; Sirtuin family, catalytic core domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG11305 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)

Experimental Summary - CG11305:

CG11305 is not perturbed in primary screen.
CG11305 is not tested in classification assay.

Cellular phenotyping(Images):

Click here to access phenotyping images of gene CG11305.

Cell Count:

CG_Number	Category	R1	R2	R3
CG11305	Primary screen	422	430	701

R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3

Primary screen data - CG11305:

SN	RN	WN	Fint1	Fint2	Fint3	Fint4	Fnum	Fmph1	Fmph2	Fmph3	Fclc	Tint1	Tint2	Tint3	Tint4	Rto1	Rto2	Rto3	Okt	Tnum	Tmph1	Tmph2	Tmph3	Tclc	CellSize
21	1	36	1.221950777	-0.294849526	0.428708556	0.483868967	-0.927032379	-7.242895539	-1.742356079	-1.951098949	-4.297712137	-0.599461551	-0.347826492	-0.856844071	0.74700217	1.288398705	0.407305328	0.467674766	0.267973219	-0.013899902	-0.012525712	-3.611160159	0.586470714	-0.198279091	-0.443396667
21	2	190	2.058508198	0.199480731	-0.252543165	-0.270192725	0.536949009	0.196736308	-0.422138922	0.344819398	0.406313009	0.562425082	1.072179204	0.800317272	0.915438822	0.077058007	-0.168793979	0.595111117	0.404189569	2.45969573	0.672421664	0.063802258	1.428354428	0.05890705	-0.410894665
21	3	100	0.593588123	0.819744736	1.54700372	0.376916811	1.228447484	0.102294298	0.234891899	-0.461802551	0.616274937	-0.757643135	0.76708815	2.565950521	1.802529611	1.721300167	1.403532127	1.195997413	-0.081031051	-0.945649531	-0.989160302	0.772017116	0.106946775	9.447183056	7.823797193

SN: Slide Number; RN: Replicate Number; WN: Well Number

Experimental Data (Classification Assay):

CG11305 is not tested in classification assay

Integrated Annotations for CG11305 :

Gene Ontology Annoations: Biological Process

Biological Process - Term	GO ID	Evidence
protein deacetylation	GO:0006476	inferred from electronic annotation with InterPro:IPR003000

Gene Ontology Annoations: Cellular Component

Cellular Component - Term	GO ID	Evidence
-

Gene Ontology Annoations: Molecular Function

Molecular Function - Term	GO ID	Evidence
NAD+ binding	GO:0070403	inferred from electronic annotation with InterPro:IPR003000 zinc ion binding

Other annotations

Database	Link
FlyBase	Click here to see CG11305 in FlyBase
FLIGHT	Click here to see CG11305 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRID	Click here to see CG11305 in BioGRID (Interaction Summary)
Off-target	Click here for Off-target data for CG11305
Entrez Gene	Entrez Gene page for CG11305
Uniprot	Uniprot page for CG11305

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Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)