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Gene Page - CG Number : CG11323
Gene Summary - CG11323:

CG11323: The gene Tubulin tyrosine ligase-like 3A is referred to in FlyBase by the symbol Dmel\TTLL3A (CG11323, FBgn0031854). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: tubulin-tyrosine ligase activity. There is experimental evidence that it is involved in the biological process: protein polyglycylation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Tubulin-tyrosine ligase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of no expression detected. Peak expression observed within 18-24 hour embryonic stages.

Gene summary for CG11323 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11323:CG11323 is perturbed in following parameters in primary screen: NuCirc NuFluct NuSize
CG11323 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11323.
Cell Count:
CG_NumberCategoryR1R2R3
CG11323Primary screen435656972
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11323:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211461.4051911380.820040010.59136104-0.642348406-0.116792124-1.330280975-1.907797094-1.050983501-1.066047597-0.213370404-0.0011658070.1747515274.0454492350.6478976581.065035091-0.042971723-0.4825093090.124798786-0.76662543-1.2320937052.6596188275.6204914827.754073222
2122102.1517772482.1308912981.5181473820.4800391741.553622960.3967603131.3176945970.578034022-0.3193777792.0531465370.5820341790.289166586-0.0583687910.0028087760.0438838350.388876441-0.2091676760.0308074290.1882453140.1214114390.7110946260.8743490731.295993146
213120-0.2785379221.659537481.1361350841.0745807241.8995568212.6464865641.2348010342.7726026923.989076466-0.0706760512.7280205460.493133108-0.2792543410.3242880350.4291989321.607587611.5743592611.7370648232.0495330764.2700842341.47081628810.722821217.686878657
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11323 is not tested in classification assay
Integrated Annotations for CG11323 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
protein polyglycylationGO:0018094inferred from direct assay
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
tubulin-tyrosine ligase activityGO:0004835inferred from sequence or structural similarity with UniProtKB:P38160
Other annotations
DatabaseLink
FlyBaseClick here to see CG11323 in FlyBase
FLIGHTClick here to see CG11323 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11323 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11323
Entrez GeneEntrez Gene page for CG11323
UniprotUniprot page for CG11323

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)