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Gene Page - CG Number : CG11324
Gene Summary - CG11324:

CG11324: The gene homer is referred to in FlyBase by the symbol Dmel\homer (CG11324, FBgn0025777). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: adult behavior; response to ethanol; regulation of locomotion; positive regulation of circadian sleep/wake cycle, sleep; behavioral response to ethanol. 21 alleles are reported. The phenotype of these alleles is annotated with: tarsal segment. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: EVH1; Pleckstrin homology-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG11324 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11324:CG11324 is perturbed in following parameters in primary screen: Rto3
CG11324 is not tested in classification assay (fluid).
CG11324 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Fint1+ Fint2+ Fint4- Rto1+(tfr) Tint1+
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11324.
Cell Count:
CG_NumberCategoryR1R2R3
CG11324Primary screen6395961031
CG11324Secondary assay80710081001
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11324:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
21147-0.1845293-0.730598375-0.831776919-0.0690754840.271559084-0.483606505-0.371641027-0.106452613-1.3341804860.889629001-0.4733593630.759912834-0.3262640010.2156852351.0551136790.929423679-0.6907818230.177621367-0.462099671-0.848681160.4396484890.8651485510.720306766
2122091.03429669-0.266206537-0.3156753660.0079411041.3185741041.5646198371.1094581191.6344608051.7549452841.406206513-0.101186604-0.1890809374.5784955264.042405112-0.124161326-0.029152044-0.770681557-0.4319300852.2966075971.2082438840.788454152-0.00077048-0.460076185
2131190.84809805-0.6494039120.5490713270.0276254330.5510711483.5112311173.5205506923.5984682064.884442484-0.3282379572.6721699981.0790082142.0236403863.3712185210.2844981921.172328210.3445963572.62037560.3812555155.6000907160.0230053299.55312897810.01854033
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11324Slide10F0.0041.3831.2931.251
CG11324Slide10O0.8240.9711.0620.991
CG11324Slide10T0.5810.9670.9140.961
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG11324 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
adult behaviorGO:0030534inferred from mutant phenotype
regulation of locomotion
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
dendriteGO:0030425inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
-
Other annotations
DatabaseLink
FlyBaseClick here to see CG11324 in FlyBase
FLIGHTClick here to see CG11324 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11324 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11324
Entrez GeneEntrez Gene page for CG11324
UniprotUniprot page for CG11324

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)