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Gene Page - CG Number : CG11325
Gene Summary - CG11325:

CG11325: The gene Gonadotropin-releasing hormone receptor is referred to in FlyBase by the symbol Dmel\GRHR (CG11325, FBgn0025595). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: adipokinetic hormone binding; peptide receptor activity; adipokinetic hormone receptor activity. There is experimental evidence that it is involved in the biological process: triglyceride homeostasis; lipid homeostasis; G-protein coupled receptor signaling pathway; lipid catabolic process; carbohydrate homeostasis. 17 alleles are reported. The phenotypes of these alleles are annotated with: adult fat body; lipid droplet. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: GPCR, rhodopsin-like; GPCR, rhodopsin-like, 7TM. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late larval stages, during early pupal stages.

Gene summary for CG11325 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11325:CG11325 is perturbed in following parameters in primary screen: NuSize
CG11325 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11325.
Cell Count:
CG_NumberCategoryR1R2R3
CG11325Primary screen464570649
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11325:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211481.056336007-0.555688007-0.7943749290.240571313-0.45549143-1.526146531-0.106369748-1.03420891-0.9328192810.3960099921.5647098650.844348061-0.5612769720.1235970541.656969763-0.316868148-0.2757554631.007435188-0.284167812-0.7827490862.7738683364.7641317523.740565941
2122080.9283296350.0182430670.087812662-0.0982906710.7760218492.0096698241.4713426851.9506392341.7432699431.021170665-0.2391971820.2047933843.0959487792.001716279-0.3539033691.227086317-0.771581574-0.463676564-0.8050833631.5132897120.1617602052.8930787790.809436536
213118-0.2522560090.4725973980.0043769110.0791847660.7690429371.8686186920.8898418711.869339272.05376499-0.145881082-0.5124952820.29956162-0.242617280.235644181-0.2571545721.5248516910.5608035420.8127429080.2211159992.304967806-0.4203494154.3996426542.786455225
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11325 is not tested in classification assay
Integrated Annotations for CG11325 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
G-protein coupled receptor signaling pathwayGO:0007186inferred from sequence or structural similarity
G-protein coupled receptor signaling pathway
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021inferred from sequence or structural similarity
integral to plasma membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
neuropeptide receptor activityGO:0008188inferred from sequence or structural similarity
G-protein coupled receptor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11325 in FlyBase
FLIGHTClick here to see CG11325 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11325 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11325
Entrez GeneEntrez Gene page for CG11325
UniprotUniprot page for CG11325

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)