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Gene Page - CG Number : CG11326
Gene Summary - CG11326:

CG11326: The gene Thrombospondin is referred to in FlyBase by the symbol Dmel\Tsp (CG11326, FBgn0031850). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: heparin binding. There is experimental evidence that it is involved in the biological process: muscle organ development; cell adhesion mediated by integrin; muscle attachment. 20 alleles are reported. The phenotypes of these alleles are annotated with: tendon cell; dorsal oblique muscle; lateral longitudinal muscle; dorsal acute muscle; embryonic/larval muscle system; ventral longitudinal muscle. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Concanavalin A-like lectin/glucanase, subgroup; Concanavalin A-like lectin/glucanases superfamily; EGF-like calcium-binding; EGF-like calcium-binding, conserved site; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Epidermal growth factor-like domain; Thrombospondin, C-terminal; Thrombospondin, type 3 repeat; Thrombospondin, type 3-like repeat; Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages, during late pupal stages.

Gene summary for CG11326 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11326:CG11326 is not perturbed in primary screen.
CG11326 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11326.
Cell Count:
CG_NumberCategoryR1R2R3
CG11326Primary screen769527961
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11326:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211500.033439398-0.481528868-0.511385476-0.0037632050.300391576-1.541461774-0.217388405-0.938618135-0.084753654-0.141268240.0926627491.2281612910.110522224-0.7095708231.933904971.09002061-0.8435763030.382346958-0.8850750320.228408849-0.237347077-0.51095536-0.423862225
212206-0.157507806-0.1234906430.2469813051.1677070150.7532390331.8695594421.6452422861.8225353651.9750288720.396299607-0.881031302-0.7322237731.6011126410.104497764-0.1866987450.6140553591.380257262.5252537491.982916011.4698347061.4438116410.836247114-0.192260529
2131161.557570397-0.2850211920.6411288590.7601105580.4471658995.6476321772.7516838014.2207224754.4941112060.9211352932.037125318-0.1696111170.9815014362.0510957320.3857801510.9224655841.5742715864.1652515110.5037398325.2031944441.18358989711.423026889.2310694
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11326 is not tested in classification assay
Integrated Annotations for CG11326 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
cell adhesion mediated by integrinGO:0033627inferred from mutant phenotype
muscle organ development
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
muscle tendon junctionGO:0005927inferred from direct assay
extracellular region
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
heparin bindingGO:0008201inferred from direct assay
calcium ion binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11326 in FlyBase
FLIGHTClick here to see CG11326 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11326 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11326
Entrez GeneEntrez Gene page for CG11326
UniprotUniprot page for CG11326

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)