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Gene Page - CG Number : CG11328
Gene Summary - CG11328:

CG11328: The gene Na+/H+ hydrogen exchanger 3 is referred to in FlyBase by the symbol Dmel\Nhe3 (CG11328, FBgn0028703). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: sodium:hydrogen antiporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport; sodium ion transport; regulation of pH. 5 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Cation/H+ exchanger; Cation/H+ exchanger, CPA1 family; Na+/H+ exchanger; Na+/H+ exchanger, isoform 6 (NHE6). Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.

Gene summary for CG11328 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11328:CG11328 is not perturbed in primary screen.
CG11328 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11328.
Cell Count:
CG11328Primary screen435341711
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11328:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11328 is not tested in classification assay
Integrated Annotations for CG11328 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
transmembrane transportGO:0055085inferred from electronic annotation with InterPro:IPR004709, InterPro:IPR006153
regulation of pH
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
perinuclear region of cytoplasmGO:0048471inferred from direct assay
integral to membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sodium:hydrogen antiporter activityGO:0015385non-traceable author statement
sodium:hydrogen antiporter activity
Other annotations
FlyBaseClick here to see CG11328 in FlyBase
FLIGHTClick here to see CG11328 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11328 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11328
Entrez GeneEntrez Gene page for CG11328
UniprotUniprot page for CG11328

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)