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Gene Page - CG Number : CG11335
Gene Summary - CG11335:

CG11335: The gene lysyl oxidase-like is referred to in FlyBase by the symbol Dmel\lox (CG11335, FBgn0039848). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: copper ion binding; protein-lysine 6-oxidase activity. Based on sequence similarity, it is predicted to be involved in the biological process: cell adhesion; cellular protein modification process. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Lysyl oxidase; Speract/scavenger receptor; Speract/scavenger receptor-related. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed during early pupal stages.

Gene summary for CG11335 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11335:CG11335 is not perturbed in primary screen.
CG11335 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11335.
Cell Count:
CG_NumberCategoryR1R2R3
CG11335Primary screen598441371
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11335:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211550.678494354-0.309208213-1.01720965-0.9309994370.2790509390.76249850.4790425680.7322477811.0853526572.543469279-0.014926103-0.0997172041.0993010520.3697060490.163554859-0.166249491-0.2253690911.028290303-0.0022498440.519180806-0.2021473880.290630682-0.204077682
2122010.9420781420.2385613070.318726293-0.5295962270.932725214-3.002341927-0.318858375-2.92336699-3.033564007-0.5635719770.308211421-0.275270674-0.19802126-0.091502922.657480084-0.262299977-1.017160095-0.603875933-1.258867626-1.8164425050.1294284340.291716466-0.765122611
213111-0.717906748-0.304078397-0.0790875171.317184171-1.268945801-0.674140464-0.964105879-0.745048885-0.940177365-0.502797978-0.377259039-0.722468337-0.546475159-0.788961453-0.4934875150.423380148-0.253674935-1.331840168-0.536885689-2.6922492872.366129432-0.065301041-0.589929925
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11335 is not tested in classification assay
Integrated Annotations for CG11335 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
cell adhesionGO:0007155inferred from sequence or structural similarity with UniProtKB:Q9Y4K0
protein modification process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
membraneGO:0016020inferred from electronic annotation with InterPro:IPR001190, InterPro:IPR017448
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein-lysine 6-oxidase activityGO:0004720inferred from sequence or structural similarity with UniProtKB:Q96JB6
protein-lysine 6-oxidase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11335 in FlyBase
FLIGHTClick here to see CG11335 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11335 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11335
Entrez GeneEntrez Gene page for CG11335
UniprotUniprot page for CG11335

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)