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Gene Page - CG Number : CG11340
Gene Summary - CG11340:

CG11340: This gene is referred to in FlyBase by the symbol Dmel\CG11340 (FBgn0039840). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: extracellular-glycine-gated chloride channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ion transport. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Gamma-aminobutyric acid A receptor; Glutamate-Gated Chloride Channel; Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding; Neurotransmitter-gated ion-channel transmembrane domain; Neurotransmitter-gated ion-channel, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed at stages throughout the larval period, in stages of adults of both sexes.

Gene summary for CG11340 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11340:CG11340 is not perturbed in primary screen.
CG11340 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11340.
Cell Count:
CG_NumberCategoryR1R2R3
CG11340Primary screen560698276
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11340:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
21158-0.21683602-0.523835937-0.0160139760.1631767280.579722959-0.354269574-1.096100089-0.4134363711.6835741141.211702134-0.219264647-0.301134775-0.3146225560.1825282120.8883447160.242676822-0.6108693320.0233404092.040087071-0.951821531-0.0272394571.1663009710.625450947
2121981.4987939280.278092362-0.275630651-0.0215151281.0184200831.4390600340.9595421731.6962397741.848383906-0.0705195891.4540514650.0030970231.038851130.288871212-0.033666850.9071220451.2861591511.8559516651.3500165521.5754189450.3800573613.6668583351.864607334
213108-0.670372009-0.444727601-1.020200549-0.95226425-0.254860547-1.005903293-0.950981722-1.159701476-2.182460231-0.933387446-1.53260075-1.076468831-0.9365495550.4405611980.5581013460.127212252-0.506941551-1.533293732-0.183149388-2.2716307995.6948483951.6183926230.837681892
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11340 is not tested in classification assay
Integrated Annotations for CG11340 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
ion transportGO:0006811inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006029, InterPro:IPR006201, InterPro:IPR018000
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
glycine-gated chloride channel complexGO:0016935inferred from sequence or structural similarity with UniProtKB:P24524
postsynaptic membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
extracellular-glycine-gated chloride channel activityGO:0016934inferred from sequence or structural similarity with UniProtKB:P24524
Other annotations
DatabaseLink
FlyBaseClick here to see CG11340 in FlyBase
FLIGHTClick here to see CG11340 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11340 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11340
Entrez GeneEntrez Gene page for CG11340
UniprotUniprot page for CG11340

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)